Cole MD, McMahon SB: The Myc oncoprotein: a critical evaluation of transactivation and target gene regulation. Oncogene. 1999, 18 (19): 2916-2924. 10.1038/sj.onc.1202748
Article
CAS
PubMed
Google Scholar
Patel JH, Loboda AP, Showe MK, Showe LC, McMahon SB: Analysis of genomic targets reveals complex functions of MYC. Nat Rev Cancer. 2004, 4 (7): 562-568. 10.1038/nrc1393
Article
CAS
PubMed
Google Scholar
Pelengaris S, Khan M, Evan G: c-MYC: more than just a matter of life and death. Nat Rev Cancer. 2002, 2 (10): 764-776. 10.1038/nrc904
Article
CAS
PubMed
Google Scholar
Adhikary S, Eilers M: Transcriptional regulation and transformation by Myc proteins. Nat Rev Mol Cell Biol. 2005, 6 (8): 635-645. 10.1038/nrm1703
Article
CAS
PubMed
Google Scholar
Mao DY, Barsyte-Lovejoy D, Ho CS, Watson JD, Stojanova A, Penn LZ: Promoter-binding and repression of PDGFRB by c-Myc are separable activities. Nucleic Acids Res. 2004, 32 (11): 3462-3468. 10.1093/nar/gkh669
Article
PubMed Central
CAS
PubMed
Google Scholar
Guccione E, Martinato F, Finocchiaro G, Luzi L, Tizzoni L, Dall' Olio V, Zardo G, Nervi C, Bernard L, Amati B: Myc-binding-site recognition in the human genome is determined by chromatin context. Nat Cell Biol. 2006, 8 (7): 764-770. 10.1038/ncb1434
Article
CAS
PubMed
Google Scholar
Gallant P, Shiio Y, Cheng PF, Parkhurst SM, Eisenman RN: Myc and Max homologs in Drosophila. Science. 1996, 274 (5292): 1523-1527. 10.1126/science.274.5292.1523
Article
CAS
PubMed
Google Scholar
Schreiber-Agus N, Stein D, Chen K, Goltz JS, Stevens L, DePinho RA: Drosophila Myc is oncogenic in mammalian cells and plays a role in the diminutive phenotype. Proc Natl Acad Sci U S A. 1997, 94 (4): 1235-1240. 10.1073/pnas.94.4.1235
Article
PubMed Central
CAS
PubMed
Google Scholar
Trumpp A, Refaeli Y, Oskarsson T, Gasser S, Murphy M, Martin GR, Bishop JM: c-Myc regulates mammalian body size by controlling cell number but not cell size. Nature. 2001, 414 (6865): 768-773. 10.1038/414768a
Article
CAS
PubMed
Google Scholar
de la Cova C, Abril M, Bellosta P, Gallant P, Johnston LA: Drosophila myc regulates organ size by inducing cell competition. Cell. 2004, 117 (1): 107-116. 10.1016/S0092-8674(04)00214-4
Article
CAS
PubMed
Google Scholar
Grewal SS, Li L, Orian A, Eisenman RN, Edgar BA: Myc-dependent regulation of ribosomal RNA synthesis during Drosophila development. Nat Cell Biol. 2005, 7 (3): 295-302. 10.1038/ncb1223
Article
CAS
PubMed
Google Scholar
Maines JZ, Stevens LM, Tong X, Stein D: Drosophila dMyc is required for ovary cell growth and endoreplication. Development. 2004, 131 (4): 775-786. 10.1242/dev.00932
Article
CAS
PubMed
Google Scholar
Moreno E, Basler K: dMyc transforms cells into super-competitors. Cell. 2004, 117 (1): 117-129. 10.1016/S0092-8674(04)00262-4
Article
CAS
PubMed
Google Scholar
Pierce SB, Yost C, Britton JS, Loo LW, Flynn EM, Edgar BA, Eisenman RN: dMyc is required for larval growth and endoreplication in Drosophila. Development. 2004, 131 (10): 2317-2327. 10.1242/dev.01108
Article
CAS
PubMed
Google Scholar
Beer S, Zetterberg A, Ihrie RA, McTaggart RA, Yang Q, Bradon N, Arvanitis C, Attardi LD, Feng S, Ruebner B, Cardiff RD, Felsher DW: Developmental context determines latency of MYC-induced tumorigenesis. PLoS Biol. 2004, 2 (11): e332- 10.1371/journal.pbio.0020332
Article
PubMed Central
PubMed
Google Scholar
Levine SS, King IF, Kingston RE: Division of labor in polycomb group repression. Trends Biochem Sci. 2004, 29 (9): 478-485. 10.1016/j.tibs.2004.07.007
Article
CAS
PubMed
Google Scholar
Ringrose L, Paro R: Epigenetic regulation of cellular memory by the Polycomb and Trithorax group proteins. Annu Rev Genet. 2004, 38: 413-443. 10.1146/annurev.genet.38.072902.091907
Article
CAS
PubMed
Google Scholar
Goodliffe JM, Wieschaus E, Cole MD: Polycomb mediates Myc autorepression and its transcriptional control of many loci in Drosophila. Genes Dev. 2005, 19 (24): 2941-2946. 10.1101/gad.1352305
Article
PubMed Central
CAS
PubMed
Google Scholar
Campbell RB, Sinclair DA, Couling M, Brock HW: Genetic interactions and dosage effects of Polycomb group genes of Drosophila. Mol Gen Genet. 1995, 246 (3): 291-300. 10.1007/BF00288601
Article
CAS
PubMed
Google Scholar
Simon J, Chiang A, Bender W: Ten different Polycomb group genes are required for spatial control of the abdA and AbdB homeotic products. Development. 1992, 114 (2): 493-505.
CAS
PubMed
Google Scholar
Boyer LA, Plath K, Zeitlinger J, Brambrink T, Medeiros LA, Lee TI, Levine SS, Wernig M, Tajonar A, Ray MK, Bell GW, Otte AP, Vidal M, Gifford DK, Young RA, Jaenisch R: Polycomb complexes repress developmental regulators in murine embryonic stem cells. Nature. 2006, 441 (7091): 349-353. 10.1038/nature04733
Article
CAS
PubMed
Google Scholar
Bracken AP, Dietrich N, Pasini D, Hansen KH, Helin K: Genome-wide mapping of Polycomb target genes unravels their roles in cell fate transitions. Genes Dev. 2006, 20 (9): 1123-1136. 10.1101/gad.381706
Article
PubMed Central
CAS
PubMed
Google Scholar
Lee TI, Jenner RG, Boyer LA, Guenther MG, Levine SS, Kumar RM, Chevalier B, Johnstone SE, Cole MF, Isono K, Koseki H, Fuchikami T, Abe K, Murray HL, Zucker JP, Yuan B, Bell GW, Herbolsheimer E, Hannett NM, Sun K, Odom DT, Otte AP, Volkert TL, Bartel DP, Melton DA, Gifford DK, Jaenisch R, Young RA: Control of developmental regulators by Polycomb in human embryonic stem cells. Cell. 2006, 125 (2): 301-313. 10.1016/j.cell.2006.02.043
Article
PubMed Central
CAS
PubMed
Google Scholar
Negre N, Hennetin J, Sun LV, Lavrov S, Bellis M, White KP, Cavalli G: Chromosomal Distribution of PcG Proteins during Drosophila Development. PLoS Biol. 2006, 4 (6): e170- 10.1371/journal.pbio.0040170
Article
PubMed Central
PubMed
Google Scholar
Tolhuis B, de Wit E, Muijrers I, Teunissen H, Talhout W, van Steensel B, van Lohuizen M: Genome-wide profiling of PRC1 and PRC2 Polycomb chromatin binding in Drosophila melanogaster. Nat Genet. 2006, 38 (6): 694-699. 10.1038/ng1792
Article
CAS
PubMed
Google Scholar
Muller J, Kassis JA: Polycomb response elements and targeting of Polycomb group proteins in Drosophila. Curr Opin Genet Dev. 2006, 16 (5): 476-484. 10.1016/j.gde.2006.08.005
Article
PubMed
Google Scholar
Pirrotta V, Poux S, Melfi R, Pilyugin M: Assembly of Polycomb complexes and silencing mechanisms. Genetica. 2003, 117 (2-3): 191-197. 10.1023/A:1022992011833
Article
CAS
PubMed
Google Scholar
Brown JL, Mucci D, Whiteley M, Dirksen ML, Kassis JA: The Drosophila Polycomb group gene pleiohomeotic encodes a DNA binding protein with homology to the transcription factor YY1. Mol Cell. 1998, 1 (7): 1057-1064. 10.1016/S1097-2765(00)80106-9
Article
CAS
PubMed
Google Scholar
Klymenko T, Papp B, Fischle W, Kocher T, Schelder M, Fritsch C, Wild B, Wilm M, Muller J: A Polycomb group protein complex with sequence-specific DNA-binding and selective methyl-lysine-binding activities. Genes Dev. 2006, 20 (9): 1110-1122. 10.1101/gad.377406
Article
PubMed Central
CAS
PubMed
Google Scholar
Mohd-Sarip A, Cleard F, Mishra RK, Karch F, Verrijzer CP: Synergistic recognition of an epigenetic DNA element by Pleiohomeotic and a Polycomb core complex. Genes Dev. 2005, 19 (15): 1755-1760. 10.1101/gad.347005
Article
PubMed Central
CAS
PubMed
Google Scholar
Mohd-Sarip A, Venturini F, Chalkley GE, Verrijzer CP: Pleiohomeotic can link polycomb to DNA and mediate transcriptional repression. Mol Cell Biol. 2002, 22 (21): 7473-7483. 10.1128/MCB.22.21.7473-7483.2002
Article
PubMed Central
CAS
PubMed
Google Scholar
Wang L, Brown JL, Cao R, Zhang Y, Kassis JA, Jones RS: Hierarchical recruitment of polycomb group silencing complexes. Mol Cell. 2004, 14 (5): 637-646. 10.1016/j.molcel.2004.05.009
Article
CAS
PubMed
Google Scholar
Brock HW, Fisher CL: Maintenance of gene expression patterns. Dev Dyn. 2005, 232 (3): 633-655. 10.1002/dvdy.20298
Article
CAS
PubMed
Google Scholar
Francis NJ, Saurin AJ, Shao Z, Kingston RE: Reconstitution of a functional core polycomb repressive complex. Mol Cell. 2001, 8 (3): 545-556. 10.1016/S1097-2765(01)00316-1
Article
CAS
PubMed
Google Scholar
Cao R, Wang L, Wang H, Xia L, Erdjument-Bromage H, Tempst P, Jones RS, Zhang Y: Role of histone H3 lysine 27 methylation in Polycomb-group silencing. Science. 2002, 298 (5595): 1039-1043. 10.1126/science.1076997
Article
CAS
PubMed
Google Scholar
Czermin B, Melfi R, McCabe D, Seitz V, Imhof A, Pirrotta V: Drosophila enhancer of Zeste/ESC complexes have a histone H3 methyltransferase activity that marks chromosomal Polycomb sites. Cell. 2002, 111 (2): 185-196. 10.1016/S0092-8674(02)00975-3
Article
CAS
PubMed
Google Scholar
Muller J, Hart CM, Francis NJ, Vargas ML, Sengupta A, Wild B, Miller EL, O'Connor MB, Kingston RE, Simon JA: Histone methyltransferase activity of a Drosophila Polycomb group repressor complex. Cell. 2002, 111 (2): 197-208. 10.1016/S0092-8674(02)00976-5
Article
CAS
PubMed
Google Scholar
Bellen HJ, Levis RW, Liao G, He Y, Carlson JW, Tsang G, Evans-Holm M, Hiesinger PR, Schulze KL, Rubin GM, Hoskins RA, Spradling AC: The BDGP gene disruption project: single transposon insertions associated with 40% of Drosophila genes. Genetics. 2004, 167 (2): 761-781. 10.1534/genetics.104.026427
Article
PubMed Central
CAS
PubMed
Google Scholar
Lukacsovich T, Asztalos Z, Awano W, Baba K, Kondo S, Niwa S, Yamamoto D: Dual-tagging gene trap of novel genes in Drosophila melanogaster. Genetics. 2001, 157 (2): 727-742.
PubMed Central
CAS
PubMed
Google Scholar
Schwartz YB, Kahn TG, Nix DA, Li XY, Bourgon R, Biggin M, Pirrotta V: Genome-wide analysis of Polycomb targets in Drosophila melanogaster. Nat Genet. 2006, 38 (6): 700-705. 10.1038/ng1817
Article
CAS
PubMed
Google Scholar
Chekmenev DS, Haid C, Kel AE: P-Match: transcription factor binding site search by combining patterns and weight matrices. Nucleic Acids Res. 2005, 33 (Web Server issue): W432-7. 10.1093/nar/gki441
Article
PubMed Central
CAS
PubMed
Google Scholar
Hulf T, Bellosta P, Furrer M, Steiger D, Svensson D, Barbour A, Gallant P: Whole-genome analysis reveals a strong positional bias of conserved dMyc-dependent E-boxes. Mol Cell Biol. 2005, 25 (9): 3401-3410. 10.1128/MCB.25.9.3401-3410.2005
Article
PubMed Central
CAS
PubMed
Google Scholar
Orian A, van Steensel B, Delrow J, Bussemaker HJ, Li L, Sawado T, Williams E, Loo LW, Cowley SM, Yost C, Pierce S, Edgar BA, Parkhurst SM, Eisenman RN: Genomic binding by the Drosophila Myc, Max, Mad/Mnt transcription factor network. Genes Dev. 2003, 17 (9): 1101-1114. 10.1101/gad.1066903
Article
PubMed Central
CAS
PubMed
Google Scholar
Srinivasan L, Atchison ML: YY1 DNA binding and PcG recruitment requires CtBP. Genes Dev. 2004, 18 (21): 2596-2601. 10.1101/gad.1228204
Article
PubMed Central
CAS
PubMed
Google Scholar
Beisel C, Imhof A, Greene J, Kremmer E, Sauer F: Histone methylation by the Drosophila epigenetic transcriptional regulator Ash1. Nature. 2002, 419 (6909): 857-862. 10.1038/nature01126
Article
CAS
PubMed
Google Scholar
Byrd KN, Shearn A: ASH1, a Drosophila trithorax group protein, is required for methylation of lysine 4 residues on histone H3. Proc Natl Acad Sci U S A. 2003, 100 (20): 11535-11540. 10.1073/pnas.1933593100
Article
PubMed Central
CAS
PubMed
Google Scholar
Klymenko T, Muller J: The histone methyltransferases Trithorax and Ash1 prevent transcriptional silencing by Polycomb group proteins. EMBO Rep. 2004, 5 (4): 373-377. 10.1038/sj.embor.7400111
Article
PubMed Central
CAS
PubMed
Google Scholar
LaJeunesse D, Shearn A: Trans-regulation of thoracic homeotic selector genes of the Antennapedia and bithorax complexes by the trithorax group genes: absent, small, and homeotic discs 1 and 2. Mech Dev. 1995, 53 (1): 123-139. 10.1016/0925-4773(95)00430-0
Article
CAS
PubMed
Google Scholar
Shearn A: The ash-1, ash-2 and trithorax genes of Drosophila melanogaster are functionally related. Genetics. 1989, 121 (3): 517-525.
PubMed Central
CAS
PubMed
Google Scholar
Tripoulas N, LaJeunesse D, Gildea J, Shearn A: The Drosophila ash1 gene product, which is localized at specific sites on polytene chromosomes, contains a SET domain and a PHD finger. Genetics. 1996, 143 (2): 913-928.
PubMed Central
CAS
PubMed
Google Scholar
Tripoulas NA, Hersperger E, La Jeunesse D, Shearn A: Molecular genetic analysis of the Drosophila melanogaster gene absent, small or homeotic discs1 (ash1). Genetics. 1994, 137 (4): 1027-1038.
PubMed Central
CAS
PubMed
Google Scholar
Bernstein BE, Mikkelsen TS, Xie X, Kamal M, Huebert DJ, Cuff J, Fry B, Meissner A, Wernig M, Plath K, Jaenisch R, Wagschal A, Feil R, Schreiber SL, Lander ES: A bivalent chromatin structure marks key developmental genes in embryonic stem cells. Cell. 2006, 125 (2): 315-326. 10.1016/j.cell.2006.02.041
Article
CAS
PubMed
Google Scholar
Gildea JJ, Lopez R, Shearn A: A screen for new trithorax group genes identified little imaginal discs, the Drosophila melanogaster homologue of human retinoblastoma binding protein 2. Genetics. 2000, 156 (2): 645-663.
PubMed Central
CAS
PubMed
Google Scholar
Shearn A, Rice T, Garen A, Gehring W: Imaginal disc abnormalities in lethal mutants of Drosophila. Proc Natl Acad Sci U S A. 1971, 68 (10): 2594-2598. 10.1073/pnas.68.10.2594
Article
PubMed Central
CAS
PubMed
Google Scholar
Bannister AJ, Zegerman P, Partridge JF, Miska EA, Thomas JO, Allshire RC, Kouzarides T: Selective recognition of methylated lysine 9 on histone H3 by the HP1 chromo domain. Nature. 2001, 410 (6824): 120-124. 10.1038/35065138
Article
CAS
PubMed
Google Scholar
Lachner M, O'Carroll D, Rea S, Mechtler K, Jenuwein T: Methylation of histone H3 lysine 9 creates a binding site for HP1 proteins. Nature. 2001, 410 (6824): 116-120. 10.1038/35065132
Article
CAS
PubMed
Google Scholar
Nakayama J, Rice JC, Strahl BD, Allis CD, Grewal SI: Role of histone H3 lysine 9 methylation in epigenetic control of heterochromatin assembly. Science. 2001, 292 (5514): 110-113. 10.1126/science.1060118
Article
CAS
PubMed
Google Scholar
Gehring WJ: A recessive lethal [l(4)29] with a homeotic effect in D. melanogaster. Drosophila Information Services. 1970, 45: 103-
Google Scholar
Girton JR, Jeon SH: Novel embryonic and adult homeotic phenotypes are produced by pleiohomeotic mutations in Drosophila. Dev Biol. 1994, 161 (2): 393-407. 10.1006/dbio.1994.1040
Article
CAS
PubMed
Google Scholar
Poux S, McCabe D, Pirrotta V: Recruitment of components of Polycomb Group chromatin complexes in Drosophila. Development. 2001, 128 (1): 75-85.
CAS
PubMed
Google Scholar
Mishra RK, Mihaly J, Barges S, Spierer A, Karch F, Hagstrom K, Schweinsberg SE, Schedl P: The iab-7 polycomb response element maps to a nucleosome-free region of chromatin and requires both GAGA and pleiohomeotic for silencing activity. Mol Cell Biol. 2001, 21 (4): 1311-1318. 10.1128/MCB.21.4.1311-1318.2001
Article
PubMed Central
CAS
PubMed
Google Scholar
Busturia A, Lloyd A, Bejarano F, Zavortink M, Xin H, Sakonju S: The MCP silencer of the Drosophila Abd-B gene requires both Pleiohomeotic and GAGA factor for the maintenance of repression. Development. 2001, 128 (11): 2163-2173.
CAS
PubMed
Google Scholar
Brown JL, Fritsch C, Mueller J, Kassis JA: The Drosophila pho-like gene encodes a YY1-related DNA binding protein that is redundant with pleiohomeotic in homeotic gene silencing. Development. 2003, 130 (2): 285-294. 10.1242/dev.00204
Article
CAS
PubMed
Google Scholar
Johnston LA, Prober DA, Edgar BA, Eisenman RN, Gallant P: Drosophila myc regulates cellular growth during development. Cell. 1999, 98 (6): 779-790. 10.1016/S0092-8674(00)81512-3
Article
CAS
PubMed
Google Scholar
Sanson B, White P, Vincent JP: Uncoupling cadherin-based adhesion from wingless signalling in Drosophila. Nature. 1996, 383 (6601): 627-630. 10.1038/383627a0
Article
PubMed
Google Scholar
Kennerdell JR, Carthew RW: Use of dsRNA-mediated genetic interference to demonstrate that frizzled and frizzled 2 act in the wingless pathway. Cell. 1998, 95 (7): 1017-1026. 10.1016/S0092-8674(00)81725-0
Article
CAS
PubMed
Google Scholar