Skip to main content

Advertisement

Figure 6 | BMC Molecular Biology

Figure 6

From: Coordinated regulation of Myc trans-activation targets by Polycomb and the Trithorax group protein Ash1

Figure 6

Ash1 protein's activities overlap those of Pc and Myc. (A) Expression levels of 8865 genes are plotted by their basal levels along the X axis and their levels upon ash1 RNAi along the Y axis. Red dots indicate genes whose levels rise with ash1 RNAi, and blue dots indicate genes whose levels decrease with ash1 RNAi. (B) Expression levels of 8865 genes are plotted by their response to ectopic Myc. Basal levels are along the X axis, and levels with ectopic Myc are along the Y axis. Genes in red are elevated by ash1 RNAi alone. Genes in blue are elevated by ectopic Myc alone, and genes in purple are elevated by both conditions individually. (C) Expression levels of 8865 genes are plotted by their response to Pc RNAi, plotted by their basal levels along the X axis and their levels with Pc RNAi along the Y axis. Genes in red are elevated by ash1 RNAi alone, genes in blue are elevated by Pc RNAi alone, and genes in purple are elevated by both conditions individually. (D) Ectopic Myc replaces Ash1 in gene activation. Changes in expression of 160 genes are shown, log2 of ratios of expression over basal, for transcripts whose levels drop with ash1 RNAi (blue bars). For each of the 169 genes, the change in expression in embryos with ash1 RNAi combined with ectopic Myc is also shown (red bars, next to blue bar for each gene).

Back to article page