Halliwell B, Gutteridge JM: Free radicals and antioxidant protection: mechanisms and significance in toxicology and disease. Hum Toxicol. 1988, 7: 7-13. 10.1177/096032718800700102
Article
CAS
PubMed
Google Scholar
Jones DP: Radical-free biology of oxidative stress. Am J Physiol Cell Physiol. 2008, 295: C849-C868. 10.1152/ajpcell.00283.2008
Article
CAS
PubMed
PubMed Central
Google Scholar
Thornalley PJ, Vasak M: Possible role for metallothionein in protection against radiation-induced oxidative stress. Kinetics and mechanism of its reaction with superoxide and hydroxyl radicals. Biochim Biophys Acta. 1985, 827: 36-44. 10.1016/0167-4838(85)90098-6
Article
CAS
PubMed
Google Scholar
Kling PG, Olsson P: Involvement of differential metallothionein expression in free radical sensitivity of RTG-2 and CHSE-214 cells. Free Radic Biol Med. 2000, 28: 1628-1637. 10.1016/S0891-5849(00)00277-X
Article
CAS
PubMed
Google Scholar
Liu J, Liu Y, Hartley D, Klaassen CD, Shehin-Johnson SE, Lucas A, Cohen SD: Metallothionein-I/II knockout mice are sensitive to acetaminophen-induced hepatotoxicity. J Pharmacol Exp Ther. 1999, 289: 580-586.
CAS
PubMed
Google Scholar
Zheng H, Liu J, Liu Y, Klaassen CD: Hepatocytes from metallothionein-I and II knock-out mice are sensitive to cadmium- and tert-butylhydroperoxide-induced cytotoxicity. Toxicol Lett. 1996, 87: 139-145. 10.1016/0378-4274(96)03770-8
Article
CAS
PubMed
Google Scholar
Olsson PE, Kling P, Erkell LJ, Kille P: Structural and functional analysis of the rainbow trout (Oncorhyncus mykiss) metallothionein-A gene. Eur J Biochem. 1995, 230: 344-349. 10.1111/j.1432-1033.1995.tb20569.x
Article
CAS
PubMed
Google Scholar
Ebinu JO, Stang SL, Teixeira C, Bottorff DA, Hooton J, Blumberg PM, Barry M, Bleakley RC, Ostergaard HL, Stone JC: Ras GRP links T-cell receptor signaling to Ras. Blood. 2000, 95: 3199-3203.
CAS
PubMed
Google Scholar
Angel P, Poting A, Mallick U, Rahmsdorf HJ, Schorpp M, Herrlich P: Induction of metallothionein and other mRNA species by carcinogens and tumor promoters in primary human skin fibroblasts. Mol Cell Biol. 1986, 6: 1760-1766.
Article
CAS
PubMed
PubMed Central
Google Scholar
Imbra RJ, Karin M: Metallothionein gene expression is regulated by serum factors and activators of protein kinase C. Mol Cell Biol. 1987, 7: 1358-1363.
Article
CAS
PubMed
PubMed Central
Google Scholar
He P, Xu M, Ren H: Cloning and functional characterization of 5′-upstream region of metallothionein-I gene from crucian carp (Carassius cuvieri). Int J Biochem Cell Biol. 2007, 39: 832-841. 10.1016/j.biocel.2007.01.008
Article
CAS
PubMed
Google Scholar
Ren H, Xu M, He P, Muto N, Itoh N, Tanaka K, Xing J, Chu M: Cloning of crucian carp (Carassius cuvieri) metallothionein-II gene and characterization of its gene promoter region. Biochem Biophys Res Commun. 2006, 342: 1297-1304. 10.1016/j.bbrc.2006.02.082
Article
CAS
PubMed
Google Scholar
Samson SL, Paramchuk WJ, Gedamu L: The rainbow trout metallothionein-B gene promoter: contributions of distal promoter elements to metal and oxidant regulation. Biochim Biophys Acta. 2001, 1517: 202-211. 10.1016/S0167-4781(00)00273-6
Article
CAS
PubMed
Google Scholar
Matsusaka T, Fujikawa K, Nishio Y, Mukaida N, Matsushima K, Kishimoto T, Akira S: Transcription factors NF-IL6 and NF-kappa B synergistically activate transcription of the inflammatory cytokines, interleukin 6 and interleukin 8. Proc Natl Acad Sci USA. 1993, 90: 10193-10197. 10.1073/pnas.90.21.10193
Article
CAS
PubMed
PubMed Central
Google Scholar
Haslinger A, Karin M: Upstream promoter element of the human metallothionein-IIA gene can act like an enhancer element. Proc Natl Acad Sci U S A. 1985, 82: 8572-8576. 10.1073/pnas.82.24.8572
Article
CAS
PubMed
PubMed Central
Google Scholar
Karin M, Haslinger A, Heguy A, Dietlin T, Imbra R: Transcriptional control mechanisms which regulate the expression of human metallothionein genes. Experientia Suppl. 1987, 52: 401-405.
Article
CAS
PubMed
Google Scholar
Scholer H, Haslinger A, Heguy A, Holtgreve H, Karin M: In vivo competition between a metallothionein regulatory element and the SV40 enhancer. Science. 1986, 232: 76-80. 10.1126/science.3006253
Article
CAS
PubMed
Google Scholar
Aparicio S, Chapman J, Stupka E, Putnam N, Chia JM, Dehal P, Christoffels A, Rash S, Hoon S, Smit A, et al: Whole-genome shotgun assembly and analysis of the genome of Fugu rubripes. Science. 2002, 297: 1301-1310. 10.1126/science.1072104
Article
CAS
PubMed
Google Scholar
Cottage AJ, Edwards YJ, Elgar G: AP1 genes in Fugu indicate a divergent transcriptional control to that of mammals. Mamm Genome. 2003, 14: 514-525. 10.1007/s00335-002-3067-5
Article
CAS
PubMed
Google Scholar
Dalton T, Palmiter RD, Andrews GK: Transcriptional induction of the mouse metallothionein-I gene in hydrogen peroxide-treated Hepa cells involves a composite major late transcription factor/antioxidant response element and metal response promoter elements. Nucleic Acids Res. 1994, 22: 5016-5023. 10.1093/nar/22.23.5016
Article
CAS
PubMed
PubMed Central
Google Scholar
Fernando LP, Andrews GK: Cloning and expression of an avian metallothionein-encoding gene. Gene. 1994, 81: 177-183.
Article
Google Scholar
Gregor PD, Sawadogo M, Roeder RG: The adenovirus major late transcription factor USF is a member of the helix-loop-helix group of regulatory proteins and binds to DNA as a dimer. Genes Dev. 1990, 4: 1730-1740. 10.1101/gad.4.10.1730
Article
CAS
PubMed
Google Scholar
Jaiswal AK: Antioxidant response element. Biochem Pharmacol. 1994, 48: 439-444. 10.1016/0006-2952(94)90272-0
Article
CAS
PubMed
Google Scholar
Ishii T, Itoh K, Takahashi S, Sato H, Yanagawa T, Katoh Y, Bannai S, Yamamoto M: Transcription factor Nrf2 coordinately regulates a group of oxidative stress-inducible genes in macrophages. J Biol Chem. 2000, 275: 16023-16029. 10.1074/jbc.275.21.16023
Article
CAS
PubMed
Google Scholar
Rushmore TH, Morton MR, Pickett CB: The antioxidant responsive element. Activation by oxidative stress and identification of the DNA consensus sequence required for functional activity. J Biol Chem. 1991, 266: 11632-11639.
CAS
PubMed
Google Scholar
Lee JM, Moehlenkamp JD, Hanson JM, Johnson JA: Nrf2-dependent activation of the antioxidant responsive element by tert-butylhydroquinone is independent of oxidative stress in IMR-32 human neuroblastoma cells. Biochem Biophys Res Commun. 2001, 280: 286-292. 10.1006/bbrc.2000.4106
Article
CAS
PubMed
Google Scholar
Andrews GK: Regulation of metallothionein gene expression by oxidative stress and metal ions. Biochem Pharmacol. 2000, 59: 95-104. 10.1016/S0006-2952(99)00301-9
Article
CAS
PubMed
Google Scholar
Venugopal R, Jaiswal AK: Nrf2 and Nrf1 in association with Jun proteins regulate antioxidant response element-mediated expression and coordinated induction of genes encoding detoxifying enzymes. Oncogene. 1998, 17: 3145-3156. 10.1038/sj.onc.1202237
Article
CAS
PubMed
Google Scholar
Venugopal R, Jaiswal AK: Nrf1 and Nrf2 positively and c-Fos and Fra1 negatively regulate the human antioxidant response element-mediated expression of NAD(P)H:quinone oxidoreductas1 gene. Proc Natl Acad Sci USA. 1996, 93: 14960-14965. 10.1073/pnas.93.25.14960
Article
CAS
PubMed
PubMed Central
Google Scholar
Chan PC, Shiu CK, Wong FW, Wong JK, Lam KL, Chan KM: Common carp metallothionein-1 gene: cDNA cloning, gene structure and expression studies. Biochim Biophys Acta. 2004, 1676: 162-171. 10.1016/j.bbaexp.2003.11.009
Article
CAS
PubMed
Google Scholar
Yan CH, Chan KM: Cloning of zebrafish metallothionein gene and characterization of its gene promoter region in HepG2 cell line. Biochim Biophys Acta. 2004, 1679: 47-58. 10.1016/j.bbaexp.2004.04.004
Article
CAS
PubMed
Google Scholar
Buico A, Cassino C, Dondero F, Vergani L, Osella D: Radical scavenging abilities of fish MT-A and mussel MT-10 metallothionein isoforms: an ESR study. J Inorg Biochem. 2008, 102: 921-927. 10.1016/j.jinorgbio.2007.12.012
Article
CAS
PubMed
Google Scholar
Chesman BS, O'Hara S, Burt GR, Langston WJ: Hepatic metallothionein and total oxyradical scavenging capacity in Atlantic cod, Gadus morhua caged in open sea contamination gradients. Aquat Toxicol. 2007, 84: 310-320. 10.1016/j.aquatox.2007.06.008
Article
CAS
PubMed
Google Scholar
Oh SH, Deagen JT, Whanger PD, Weswig PH: Biological function of metallothionein. V. Its induction in rats by various stresses. Am J Physiol. 1978, 234: E282-E285.
CAS
PubMed
Google Scholar
Dalton TP, Li Q, Bittel D, Liang L, Andrews GK: Oxidative stress activates metal-responsive transcription factor-1 binding activity. Occupancy in vivo of metal response elements in the metallothionein-I gene promoter. J Biol Chem. 1996, 271: 26233-26241. 10.1074/jbc.271.42.26233
Article
CAS
PubMed
Google Scholar
Dalton TP, Solis WA, Nebert DW, Carvan MJ: Characterization of the MTF-1 transcription factor from zebrafish and trout cells. Comp Biochem Physiol B. 2000, 126: 325-335. 10.1016/S0305-0491(00)00182-6
Article
CAS
PubMed
Google Scholar
Lee W, Haslinger A, Karin M, Tijan R: Activation of transcription by two factors that bind promoter and enhancer sequences of the human metallothionein gene and SV40. Nature. 1987, 325: 368-372. 10.1038/325368a0
Article
CAS
PubMed
Google Scholar
Studer R, Vogt CP, Cavigelli M, Hunziker PE, Kägi JH: Metallothionein accretion in human hepatic cells is linked to cellular proliferation. Biochem J. 1997, 328: 63-67.
Article
CAS
PubMed
PubMed Central
Google Scholar
Kling P: Metallothionein regulation and function in teleosts during metal- and free radical exposure. 2001, Umea University, Umea, Sweden: Doctoral thesis,
Google Scholar
Allen RG, Venkatraj VS: Oxidants and antioxidants in development and differentiation. J Nutr. 1992, 122: 631-635.
CAS
PubMed
Google Scholar
Ye B, Maret W, Vallee BL: Zinc metallothionein imported into liver mitochondria modulates respiration. Proc Natl Acad Sci USA. 2001, 98: 2317-2322. 10.1073/pnas.041619198
Article
CAS
PubMed
PubMed Central
Google Scholar
Klampfer L, Lee TH, Hsu W, Vilcek J, Chen-Kiang S: NF-IL6 and AP-1 cooperatively modulate the activation of the TSG-6 gene by tumor necrosis factor alpha and interleukin-1. Mol Cell Biol. 1994, 14: 6561-6569.
Article
CAS
PubMed
PubMed Central
Google Scholar
Hsu W, Kerppola TK, Chen PL, Curran T, Chen-Kiang S: Fos and Jun repress transcription activation by NF-IL6 through association at the basic zipper region. Mol Cell Biol. 1994, 14: 268-276.
Article
CAS
PubMed
PubMed Central
Google Scholar
Kang SS, Woo SS, Im J, Yang JS, Yun CH, Ju HR, Son CG, Moon EY, Han SH: Human placenta promotes IL-8 expression through activation of JNK/SAPK and transcription factors NF-kappaB and AP-1 in PMA-differentiated THP-1 cells. Int Immunopharmacol. 2007, 7: 1488-1495. 10.1016/j.intimp.2007.07.011
Article
CAS
PubMed
Google Scholar
Ondrey FG, Dong G, Sunwoo J, Chen Z, Wolf JS, Crowl-Bancroft CV, Mukaida N, Van Waes C: Constitutive activation of transcription factors NF-(kappa)B, AP-1, and NF-IL6 in human head and neck squamous cell carcinoma cell lines that express pro-inflammatory and pro-angiogenic cytokines. Mol Carcinog. 1999, 26: 119-129. 10.1002/(SICI)1098-2744(199910)26:2<119::AID-MC6>3.0.CO;2-N
Article
CAS
PubMed
Google Scholar
Kanekiyo M, Itoh N, Kawasaki A, Matsuda K, Nakanishi T, Tanaka K: Metallothionein is required for zinc-induced expression of the macrophage colony stimulating factor gene. J Cell Biochem. 2002, 86: 145-153. 10.1002/jcb.10202
Article
CAS
PubMed
Google Scholar
Kanekiyo M, Itoh N, Kawasaki A, Matsuyama A, Matsuda K, Nakanishi T, Tanaka K: Metallothionein modulates lipopolysaccharide-stimulated tumour necrosis factor expression in mouse peritoneal macrophages. Biochem J. 2002, 361: 363-369. 10.1042/0264-6021:3610363
Article
CAS
PubMed
PubMed Central
Google Scholar
Vergani L, Lanza C, Borghi C, Scarabelli L, Panfoli I, Burlando B, Dondero F, Viarengo A, Gallo G: Efects of growth hormone and cadmium on the transcription regulation of two metallothionein isoforms. Mol Cell Endocrinol. 2007, 263: 29-37. 10.1016/j.mce.2006.08.010
Article
CAS
PubMed
Google Scholar
Schmittgen TD, Livak KJ: Analyzing real-time PCR data by the comparative C(T) method. Nat Protoc. 2008, 3: 1101-1108. 10.1038/nprot.2008.73
Article
CAS
PubMed
Google Scholar