Champoux JJ: DNA topoisomerases: structure, function, and mechanism. Annu Rev Biochem. 2001, 70: 369-413. 10.1146/annurev.biochem.70.1.369
Article
CAS
PubMed
Google Scholar
Topcu Z: DNA topoisomerases as targets for anticancer drugs. J Clin Pharm Ther. 2001, 26 (6): 405-416. 10.1046/j.1365-2710.2001.00368.x
Article
CAS
PubMed
Google Scholar
Dingemans AM, Pinedo HM, Giaccone G: Clinical resistance to topoisomerase-targeted drugs. Biochim Biophys Acta. 1998, 1400 (1-3): 275-288.
Article
CAS
PubMed
Google Scholar
Lage H, Helmbach H, Dietel M, Schadendorf D: Modulation of DNA topoisomerase II activity and expression in melanoma cells with acquired drug resistance. Br J Cancer. 2000, 82 (2): 488-91. 10.1054/bjoc.1999.0947
Article
PubMed Central
CAS
PubMed
Google Scholar
Son YS, Suh JM, Ahn SH, Kim JC, Yi JY, Hur KC, Hong WS, Muller MT, Chung IK: Reduced activity of topoisomerase II in an Adriamycin-resistant human stomach-adenocarcinoma cell line. Cancer Chemother Pharmacol. 1998, 41 (5): 353-360. 10.1007/s002800050751
Article
CAS
PubMed
Google Scholar
Hochhauser D, Stanway CA, Harris AL, Hickson ID: Cloning and characterization of the 5'-flanking region of the Human Topoisomerase IIa gene. J Biol Chem. 1992, 267 (26, Sept 15): 18961-18965.
CAS
PubMed
Google Scholar
Isaacs RJ, Davies SL, Sandri MI, Redwood C, Wells NJ, Hickson ID: Physiological regulation of eukaryotic topoisomerase II. Biochimica et Biophysica Acta. 1998, 1400: 121-137.
Article
CAS
PubMed
Google Scholar
Kadonaga JT, Carner KR, Masiarz FR, Tjian R: Isolation of cDNA encoding transcription factor Sp1 and functional analysis of the DNA binding domain. Cell. 1987, 51 (6): 1079-90 Issn: 0092-8674. 10.1016/0092-8674(87)90594-0
Article
CAS
PubMed
Google Scholar
Magan N, Szremska AP, Isaacs RJ, Stowell KM: Modulation of DNA topoisomerase II alpha promoter activity by members of the Sp (specificity protein) and NF-Y (nuclear factor Y) families of transcription factors. Biochem J. 2003, 374 (Pt 3): 723-729. 10.1042/BJ20030032
Article
PubMed Central
CAS
PubMed
Google Scholar
Su W, Jackson S, Tjian R, Echols H: DNA looping between sites for transcriptional activation: self-association of DNA-bound Sp1. Genes Dev. 1991, 5 (5): 820-826.
Article
CAS
PubMed
Google Scholar
Majello B, De Luca P, Hagen G, Suske G, Lania L: Different members of the Sp1 multigene family exert opposite transcriptional regulation of the long terminal repeat of HIV-1. Nucleic Acids Res. 1994, 22 (23): 4914-21 Issn: 0305-1048. 10.1093/nar/22.23.4914
Article
PubMed Central
CAS
PubMed
Google Scholar
Yu B, Datta PK, Bagchi S: Stability of the Sp3-DNA complexis promoter-specific: Sp3 efficiently competes with Sp1 for binding to promoters containing multiple Sp-sites. Nucleic Acids Res. 2003, 31 (18): 5368-5376. 10.1093/nar/gkg706
Article
PubMed Central
CAS
PubMed
Google Scholar
Woodcock CL, Dimitrov S: Higher-order structure of chromatin and chromosomes. Curr Opin Genet Dev. 2001, 11 (2): 130-135. 10.1016/S0959-437X(00)00169-6
Article
CAS
PubMed
Google Scholar
Dekker J, Rippe K, Dekker M, Kleckner N: Capturing chromosome conformation. Science. 2002, 295 (5558): 1306-1311. 10.1126/science.1067799
Article
CAS
PubMed
Google Scholar
Mastrangelo IA, Courey AJ, Wall JS, Jackson SP, Hough PV: DNA looping and Sp1 multimer links: a mechanism for transcriptional synergism and enhancement. Proc Natl Acad Sci U S A. 1991, 88 (13): 5670-5674. 10.1073/pnas.88.13.5670
Article
PubMed Central
CAS
PubMed
Google Scholar
Kubo T, Kohno K, Ohga T, Taniguchi K, Kawanami K, Wada M, Kuwano M: DNA topoisomerase II alpha gene expression under transcriptional control in etoposide/teniposide-resistant human cancer cells. Cancer Res. 1995, 55 (17): 3860-3864.
CAS
PubMed
Google Scholar
Isaacs RJ, Harris, A. L. and Hickson, I. D.: Regulation of the Human topoisomerase IIa gene promoter in Confluence-arrested cells. The Journal of Biological Chemistry. 1996, 271 (12): 16741-16747.
CAS
PubMed
Google Scholar
Allen KA, Williams AO, Isaacs RJ, Stowell KM: Down-regulation of human topoisomerase IIalpha correlates with altered expression of transcriptional regulators NF-YA and Sp1. Anticancer Drugs. 2004, 15 (4): 357-362. 10.1097/00001813-200404000-00008
Article
CAS
PubMed
Google Scholar
Andrulis ED, Neiman AM, Zappulla DC, Sternglanz R: Perinuclear localization of chromatin facilitates transcriptional silencing. Nature. 1998, 394 (6693): 592-595. 10.1038/29100
Article
CAS
PubMed
Google Scholar
Cimbora DM, Groudine M: The control of mammalian DNA replication: a brief history of space and timing. Cell. 2001, 104 (5): 643-646.
CAS
PubMed
Google Scholar
Cremer M, von Hase J, Volm T, Brero A, Kreth G, Walter J, Fischer C, Solovei I, Cremer C, Cremer T: Non-random radial higher-order chromatin arrangements in nuclei of diploid human cells. Chromosome Res. 2001, 9 (7): 541-567. 10.1023/A:1012495201697
Article
CAS
PubMed
Google Scholar
Gasser SM: Positions of potential: nuclear organization and gene expression. Cell. 2001, 104 (5): 639-642. 10.1016/S0092-8674(01)00259-8
Article
CAS
PubMed
Google Scholar
Yoon JH, Kim JK, Rha GB, Oh M, Park SH, Seong RH, Hong SH, Park SD: Sp1 mediates cell proliferation-dependent regulation of rat DNA topoisomerase IIalpha gene promoter. Biochem J. 1999, 344 (Pt 2): 367-374. 10.1042/0264-6021:3440367
Article
PubMed Central
CAS
PubMed
Google Scholar
Biggs JR, Kudlow JE, Kraft AS: The role of the transcription factor Sp1 in regulating the expression of the WAF1/CIP1 gene in U937 leukemic cells. J Biol Chem. 1996, 271 (2): 901-6 Issn: 0021-9258. 10.1074/jbc.271.2.901
Article
CAS
PubMed
Google Scholar
Li JM, Nichols MA, Chandrasekharan S, Xiong Y, Wang XF: Transforming growth factor beta activates the promoter of cyclin-dependent kinase inhibitor p15INK4B through an Sp1 consensus site. J Biol Chem. 1995, 270 (45): 26750-3 Issn: 0021-9258. 10.1074/jbc.270.45.26750
Article
CAS
PubMed
Google Scholar
McEwen DG, Ornitz DM: Regulation of the fibroblast growth factor receptor 3 promoter and intron I enhancer by Sp1 family transcription factors. J Biol Chem. 1998, 273 (9): 5349-5357. 10.1074/jbc.273.9.5349
Article
CAS
PubMed
Google Scholar
Noti JD, Johnson AK, Dillon JD: Structural and functional characterization of the leukocyte integrin gene CD11d. Essential role of Sp1 and Sp3. 1997
Google Scholar
De Luca P, Majello B, Lania L: Sp3 represses transcription when tethered to promoter DNA or targeted to promoter proximal RNA. J Biol Chem. 1996, 271 (15): 8533-8536. 10.1074/jbc.271.15.8533
Article
CAS
PubMed
Google Scholar
Suske G: The Sp-family of transcription factors. Gene. 1999, 238 (2): 291-300. 10.1016/S0378-1119(99)00357-1
Article
CAS
PubMed
Google Scholar
Ammanamanchi S, Brattain MG: Sp3 is a transcriptional repressor of transforming growth factor-beta receptors. J Biol Chem. 2001, 276 (5): 3348-3352. 10.1074/jbc.M002462200
Article
CAS
PubMed
Google Scholar
Hasleton MD, Ibbitt JC, Hurst HC: Characterization of the human activator protein-2gamma (AP-2gamma) gene: control of expression by Sp1/Sp3 in breast tumour cells. Biochem J. 2003, 373 (Pt 3): 925-932. 10.1042/BJ20030388
Article
PubMed Central
CAS
PubMed
Google Scholar
Mo YY, Wang Q, Beck WT: Down-regulation of topoisomerase IIalpha in CEM cells selected for merbarone resistance is associated with reduced expression of Sp3. Cancer Res. 1997, 57 (22): 5004-5008.
CAS
PubMed
Google Scholar
Li N, Seetharam S, Seetharam B: Characterization of the human transcobalamin II promoter. A proximal GC/GT box is a dominant negative element. J Biol Chem. 1998, 273 (26): 16104-16111. 10.1074/jbc.273.26.16104
Article
CAS
PubMed
Google Scholar
Conn KJ, Rich CB, Jensen DE, Fontanilla MR, Bashir MM, Rosenbloom J, Foster JA: Insulin-like growth factor-I regulates transcription of the elastin gene through a putative retinoblastoma control element. A role for Sp3 acting as a repressor of elastin gene transcription. J Biol Chem. 1996, 271 (46): 28853-28860. 10.1074/jbc.271.46.28853
Article
CAS
PubMed
Google Scholar
Chadjichristos C, Ghayor C, Kypriotou M, Martin G, Renard E, Ala-Kokko L, Suske G, de Crombrugghe B, Pujol JP, Galera P: Sp1 and Sp3 transcription factors mediate interleukin-1 beta down-regulation of human type II collagen gene expression in articular chondrocytes. J Biol Chem. 2003, 278 (41): 39762-72 Epub 2003 Jul 29. 10.1074/jbc.M303541200
Article
CAS
PubMed
Google Scholar
Nicolas M, Noe V, Ciudad CJ: Transcriptional regulation of the human Sp1 gene promoter by the specificity protein (Sp) family members nuclear factor Y (NF-Y) and E2F. Biochem J. 2003, 371 (Pt 2): 265-275. 10.1042/BJ20021166
Article
PubMed Central
CAS
PubMed
Google Scholar
Herbomel P, Bourachot B, Yaniv M: Two Distinct Enhancers with Different Cell Specificities Coexist in the Regulatory Region of Polyoma. Cell. 1984, 39: 653-662. 10.1016/0092-8674(84)90472-0
Article
CAS
PubMed
Google Scholar
Davis BJ: Disc Electrophoresis. Ii. Method And Application To Human Serum Proteins. Ann N Y Acad Sci. 1964, 121: 404-427. 10.1111/j.1749-6632.1964.tb14213.x
Article
CAS
PubMed
Google Scholar
Laemmli UK: Cleavage of Structural proteins during the assembly of the head of Bacteriophage T4. Nature. 1970, 227: 680-685. 10.1038/227680a0
Article
CAS
PubMed
Google Scholar
Ornstein L: Disc Electrophoresis. I. Background And Theory. Ann N Y Acad Sci. 1964, 121: 321-349. 10.1111/j.1749-6632.1964.tb14207.x
Article
CAS
PubMed
Google Scholar