Pan Q, Shai O, Lee LJ, Frey BJ, Blencowe BJ: Deep surveying of alternative splicing complexity in the human transcriptome by high-throughput sequencing. Nat Genet. 2008, 40: 1413-1415. 10.1038/ng.259
Article
CAS
PubMed
Google Scholar
Wang ET, Sandberg R, Luo S, Khrebtukova I, Zhang L, Mayr C, Kingsmore SF, Schroth GP, Burge CB: Alternative isoform regulation in human tissue transcriptomes. Nature. 2008, 456: 470-476. 10.1038/nature07509
Article
CAS
PubMed
PubMed Central
Google Scholar
Salz HK: Sex determination in insects: a binary decision based on alternative splicing. Curr Opin Genet Dev. 2011, 21: 395-400. 10.1016/j.gde.2011.03.001
Article
CAS
PubMed
PubMed Central
Google Scholar
Lopez AJ: Alternative splicing of pre-mRNA: developmental consequences and mechanisms of regulation. Annu Rev Genet. 1998, 32: 279-305. 10.1146/annurev.genet.32.1.279
Article
CAS
PubMed
Google Scholar
Black DL: Mechanisms of alternative pre-messenger RNA splicing. Annu Rev Biochem. 2003, 72: 291-336. 10.1146/annurev.biochem.72.121801.161720
Article
CAS
PubMed
Google Scholar
Nilsen TW, Graveley BR: Expansion of the eukaryotic proteome by alternative splicing. Nature. 2010, 463: 457-463. 10.1038/nature08909
Article
CAS
PubMed
PubMed Central
Google Scholar
Faustino NA, Cooper TA: Pre-mRNA splicing and human disease. Genes Dev. 2003, 17: 419-437. 10.1101/gad.1048803
Article
CAS
PubMed
Google Scholar
Calarco JA, Zhen M, Blencowe BJ: Networking in a global world: establishing functional connections between neural splicing regulators and their target transcripts. RNA. 2011, 17: 775-791. 10.1261/rna.2603911
Article
CAS
PubMed
PubMed Central
Google Scholar
Kuroyanagi H: Fox-1 family of RNA-binding proteins. Cell Mol Life Sci. 2009, 66: 3895-3907. 10.1007/s00018-009-0120-5
Article
CAS
PubMed
PubMed Central
Google Scholar
Barreau C, Paillard L, Mereau A, Osborne HB: Mammalian CELF/Bruno-like RNA-binding proteins: molecular characteristics and biological functions. Biochimie. 2006, 88: 515-525. 10.1016/j.biochi.2005.10.011
Article
CAS
PubMed
Google Scholar
Hinman MN, Lou H: Diverse molecular functions of Hu proteins. Cell Mol Life Sci. 2008, 65: 3168-3181. 10.1007/s00018-008-8252-6
Article
CAS
PubMed
PubMed Central
Google Scholar
Pascual M, Vicente M, Monferrer L, Artero R: The Muscleblind family of proteins: an emerging class of regulators of developmentally programmed alternative splicing. Differentiation. 2006, 74: 65-80. 10.1111/j.1432-0436.2006.00060.x
Article
CAS
PubMed
Google Scholar
Long JC, Caceres JF: The SR protein family of splicing factors: master regulators of gene expression. Biochem J. 2009, 417: 15-27. 10.1042/BJ20081501
Article
CAS
PubMed
Google Scholar
Li Q, Lee JA, Black DL: Neuronal regulation of alternative pre-mRNA splicing. Nat Rev Neurosci. 2007, 8: 819-831. 10.1038/nrn2237
Article
CAS
PubMed
Google Scholar
Warzecha CC, Sato TK, Nabet B, Hogenesch JB, Carstens RP: ESRP1 and ESRP2 are epithelial cell-type-specific regulators of FGFR2 splicing. Mol Cell. 2009, 33: 591-601. 10.1016/j.molcel.2009.01.025
Article
CAS
PubMed
PubMed Central
Google Scholar
Luco RF, Pan Q, Tominaga K, Blencowe BJ, Pereira-Smith OM, Misteli T: Regulation of alternative splicing by histone modifications. Science. 2010, 327: 996-1000. 10.1126/science.1184208
Article
CAS
PubMed
PubMed Central
Google Scholar
Allemand E, Batsche E, Muchardt C: Splicing, transcription, and chromatin: a menage a trois. Curr Opin Genet Dev. 2008, 18: 145-151. 10.1016/j.gde.2008.01.006
Article
CAS
PubMed
Google Scholar
Alexander R, Beggs JD: Cross-talk in transcription, splicing and chromatin: who makes the first call?. Biochem Soc Trans. 2010, 38: 1251-1256. 10.1042/BST0381251
Article
CAS
PubMed
Google Scholar
Leroy O, Wang J, Maurage CA, Parent M, Cooper T, Buee L, Sergeant N, Andreadis A, Caillet-Boudin ML: Brain-specific change in alternative splicing of Tau exon 6 in myotonic dystrophy type 1. Biochim Biophys Acta. 2006, 1762: 460-467. 10.1016/j.bbadis.2005.12.003
Article
CAS
PubMed
Google Scholar
Ho TH, Charlet BN, Poulos MG, Singh G, Swanson MS, Cooper TA: Muscleblind proteins regulate alternative splicing. EMBO J. 2004, 23: 3103-3112. 10.1038/sj.emboj.7600300
Article
CAS
PubMed
PubMed Central
Google Scholar
Kino Y, Washizu C, Oma Y, Onishi H, Nezu Y, Sasagawa N, Nukina N, Ishiura S: MBNL and CELF proteins regulate alternative splicing of the skeletal muscle chloride channel CLCN1. Nucleic Acids Res. 2009, 37: 6477-6490. 10.1093/nar/gkp681
Article
CAS
PubMed
PubMed Central
Google Scholar
Warf MB, Diegel JV, von Hippel PH, Berglund JA: The protein factors MBNL1 and U2AF65 bind alternative RNA structures to regulate splicing. Proc Natl Acad Sci USA. 2009, 106: 9203-9208. 10.1073/pnas.0900342106
Article
CAS
PubMed
PubMed Central
Google Scholar
Kalsotra A, Xiao X, Ward AJ, Castle JC, Johnson JM, Burge CB, Cooper TA: A postnatal switch of CELF and MBNL proteins reprograms alternative splicing in the developing heart. Proc Natl Acad Sci USA. 2008, 105: 20333-20338. 10.1073/pnas.0809045105
Article
CAS
PubMed
PubMed Central
Google Scholar
Larizza L, Gervasini C, Natacci F, Riva P: Developmental abnormalities and cancer predisposition in neurofibromatosis type 1. Curr Mol Med. 2009, 9: 634-653. 10.2174/156652409788488801
Article
CAS
PubMed
Google Scholar
Yunoue S, Tokuo H, Fukunaga K, Feng L, Ozawa T, Nishi T, Kikuchi A, Hattori S, Kuratsu J, Saya H, Araki N: Neurofibromatosis type I tumor suppressor neurofibromin regulates neuronal differentiation via its GTPase-activating protein function toward Ras. J Biol Chem. 2003, 278: 26958-26969. 10.1074/jbc.M209413200
Article
CAS
PubMed
Google Scholar
Andersen LB, Ballester R, Marchuk DA, Chang E, Gutmann DH, Saulino AM, Camonis J, Wigler M, Collins FS: A conserved alternative splice in the von Recklinghausen neurofibromatosis (NF1) gene produces two neurofibromin isoforms, both of which have GTPase-activating protein activity. Mol Cell Biol. 1993, 13: 487-495.
Article
CAS
PubMed
PubMed Central
Google Scholar
Barron VA, Zhu H, Hinman MN, Ladd AN, Lou H: The neurofibromatosis type I pre-mRNA is a novel target of CELF protein-mediated splicing regulation. Nucleic Acids Res. 2010, 38: 253-264. 10.1093/nar/gkp766
Article
CAS
PubMed
PubMed Central
Google Scholar
Zhou HL, Hinman MN, Barron VA, Geng C, Zhou G, Luo G, Siegel RE, Lou H: Hu proteins regulate alternative splicing by inducing localized histone hyperacetylation in an RNA-dependent manner. Proc Natl Acad Sci USA. 2011, 108: E627-E625. 10.1073/pnas.1103344108
Article
CAS
PubMed
PubMed Central
Google Scholar
Zhu H, Hinman MN, Hasman RA, Mehta P, Lou H: Regulation of neuron-specific alternative splicing of neurofibromatosis type 1 pre-mRNA. Mol Cell Biol. 2008, 28: 1240-1251. 10.1128/MCB.01509-07
Article
CAS
PubMed
PubMed Central
Google Scholar
Huynh DP, Nechiporuk T, Pulst SM: Alternative transcripts in the mouse neurofibromatosis type 2 (NF2) gene are conserved and code for schwannomins with distinct C-terminal domains. Hum Mol Genet. 1994, 3: 1075-1079. 10.1093/hmg/3.7.1075
Article
CAS
PubMed
Google Scholar
Gutmann DH, Zhang Y, Hirbe A: Developmental regulation of a neuron-specific neurofibromatosis 1 isoform. Ann Neurol. 1999, 46: 777-782. 10.1002/1531-8249(199911)46:5<777::AID-ANA15>3.0.CO;2-H
Article
CAS
PubMed
Google Scholar
Fernandez-Costa JM, Llamusi MB, Garcia-Lopez A, Artero R: Alternative splicing regulation by Muscleblind proteins: from development to disease. Biol Rev Camb Philos Soc. 2011, 86: 947-958. 10.1111/j.1469-185X.2011.00180.x
Article
PubMed
Google Scholar
Kanadia RN, Johnstone KA, Mankodi A, Lungu C, Thornton CA, Esson D, Timmers AM, Hauswirth WW, Swanson MS: A muscleblind knockout model for myotonic dystrophy. Science. 2003, 302: 1978-1980. 10.1126/science.1088583
Article
CAS
PubMed
Google Scholar
Hao M, Akrami K, Wei K, De Diego C, Che N, Ku JH, Tidball J, Graves MC, Shieh PB, Chen F: Muscleblind-like 2 (Mbnl2) -deficient mice as a model for myotonic dystrophy. Dev Dyn. 2008, 237: 403-410. 10.1002/dvdy.21428
Article
CAS
PubMed
Google Scholar
Du H, Cline MS, Osborne RJ, Tuttle DL, Clark TA, Donohue JP, Hall MP, Shiue L, Swanson MS, Thornton CA, Ares M: Aberrant alternative splicing and extracellular matrix gene expression in mouse models of myotonic dystrophy. Nat Struct Mol Biol. 2010, 17: 187-193. 10.1038/nsmb.1720
Article
CAS
PubMed
PubMed Central
Google Scholar
Kanadia RN, Urbinati CR, Crusselle VJ, Luo D, Lee YJ, Harrison JK, Oh SP, Swanson MS: Developmental expression of mouse muscleblind genes Mbnl1, Mbnl2 and Mbnl3. Gene Expr Patterns. 2003, 3: 459-462. 10.1016/S1567-133X(03)00064-4
Article
CAS
PubMed
Google Scholar
Hino S, Kondo S, Sekiya H, Saito A, Kanemoto S, Murakami T, Chihara K, Aoki Y, Nakamori M, Takahashi MP, Imaizumi K: Molecular mechanisms responsible for aberrant splicing of SERCA1 in myotonic dystrophy type 1. Hum Mol Genet. 2007, 16: 2834-2843. 10.1093/hmg/ddm239
Article
CAS
PubMed
Google Scholar
Miller JW, Urbinati CR, Teng-Umnuay P, Stenberg MG, Byrne BJ, Thornton CA, Swanson MS: Recruitment of human muscleblind proteins to (CUG)(n) expansions associated with myotonic dystrophy. EMBO J. 2000, 19: 4439-4448. 10.1093/emboj/19.17.4439
Article
CAS
PubMed
PubMed Central
Google Scholar
Kino Y, Mori D, Oma Y, Takeshita Y, Sasagawa N, Ishiura S: Muscleblind protein, MBNL1/EXP, binds specifically to CHHG repeats. Hum Mol Genet. 2004, 13: 495-507. 10.1093/hmg/ddh056
Article
CAS
PubMed
Google Scholar
Warf MB, Berglund JA: MBNL binds similar RNA structures in the CUG repeats of myotonic dystrophy and its pre-mRNA substrate cardiac troponin T. RNA. 2007, 13: 2238-2251. 10.1261/rna.610607
Article
CAS
PubMed
PubMed Central
Google Scholar
Yuan Y, Compton SA, Sobczak K, Stenberg MG, Thornton CA, Griffith JD, Swanson MS: Muscleblind-like 1 interacts with RNA hairpins in splicing target and pathogenic RNAs. Nucleic Acids Res. 2007, 35: 5474-5486. 10.1093/nar/gkm601
Article
CAS
PubMed
PubMed Central
Google Scholar
Goers ES, Purcell J, Voelker RB, Gates DP, Berglund JA: MBNL1 binds GC motifs embedded in pyrimidines to regulate alternative splicing. Nucleic Acids Res. 2010, 38: 2467-2484. 10.1093/nar/gkp1209
Article
CAS
PubMed
PubMed Central
Google Scholar
Gitler AD, Epstein JA: Regulating heart development: the role of Nf1. Cell Cycle. 2003, 2: 96-98.
Article
CAS
PubMed
Google Scholar
Dhaenens CM, Tran H, Frandemiche ML, Carpentier C, Schraen-Maschke S, Sistiaga A, Goicoechea M, Eddarkaoui S, Van Brussels E, Obriot H: Mis-splicing of Tau exon 10 in myotonic dystrophy type 1 is reproduced by overexpression of CELF2 but not by MBNL1 silencing. Biochim Biophys Acta. 2011, 1812: 732-742. 10.1016/j.bbadis.2011.03.010
Article
CAS
PubMed
Google Scholar
Ladd AN, Charlet N, Cooper TA: The CELF family of RNA binding proteins is implicated in cell-specific and developmentally regulated alternative splicing. Mol Cell Biol. 2001, 21: 1285-1296. 10.1128/MCB.21.4.1285-1296.2001
Article
CAS
PubMed
PubMed Central
Google Scholar
Russo AF, Lanigan TM, Sullivan BE: Neuronal properties of a thyroid C-cell line: partial repression by dexamethasone and retinoic acid. Mol Endocrinol. 1992, 6: 207-218. 10.1210/me.6.2.207
CAS
PubMed
Google Scholar
Russo AF, Clark MS, Durham PL: Thyroid parafollicular cells. An accessible model for the study of serotonergic neurons. Mol Neurobiol. 1996, 13: 257-276. 10.1007/BF02740626
Article
CAS
PubMed
Google Scholar
Dignam JD, Lebovitz RM, Roeder RG: Accurate transcription initiation by RNA polymerase II in a soluble extract from isolated mammalian nuclei. Nucleic Acids Res. 1983, 11: 1475-1489. 10.1093/nar/11.5.1475
Article
CAS
PubMed
PubMed Central
Google Scholar
Terenzi F, Ladd AN: Conserved developmental alternative splicing of muscleblind-like (MBNL) transcripts regulates MBNL localization and activity. RNA Biol. 2010, 7: 43-55. 10.4161/rna.7.1.10401
Article
CAS
PubMed
Google Scholar