Protein
|
Amino Acid
|
Amino Acid
|
Amino Acid
|
---|
MIOX3
|
Val 109
|
Arg-116
|
Gln-211
|
MIOX2
|
Val-61
|
Arg-68
|
Gln-163
|
MIOX1
|
Glu-66
|
Arg-71
|
Gln-168
|
musculus
|
Thr-32
|
Arg-39
|
Gln-136
|
- The main chain hydrogen bonds involving Arg and Gln are predicted to be conserved in all four proteins. MIOX2 and MIOX3 protein share a substitution of Val for Thr disrupting the main chain hydrogen bond found at that location in the Mus musculus protein. MIOX1 protein has a conservative substitution of Glu for Thr suggesting the preservation of that main chain hydrogen bond.