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Table 1 List of known genes located within 100 kb of the DNA sequences isolated after ChIP that are putative targets of p63.

From: Novel in vivo targets of ΔNp63 in keratinocytes identified by a modified chromatin immunoprecipitation approach

p63 Binding Fragment Chromosome Number Nearest gene Location Description Accession Number Gene Ontology
A2 3p12 SHQ1 3' end SHQ1 homolog (S. cervisiae) NM_018130 RNA processing
A4 7p15 AHR* intron 10 Aryl hydrocarbon receptor NM_001621 Transcription
A5 13q22 KLF12 intron 6 Kruppel-like factor 12 NM_0072498 Transcription
A6 11p15 ARNTL* 5'end Ayrl hydrocarbon receptor nuclear translocator-like NM_001178 Transcription
B2 11cenq22 ME3 intron 1 Malic enzyme 3 NM_001014811 Oxioreductase activity
B5 12q13 STAT6* intron 19 Signal transducer and activator of transcription 6 NM_003153 Transcription
C3 7p15.1 ZNRF2* intron 1 Zinc and ring finger 2 NM_147128 Ubiquitin ligase activity
C6 6q22.31 HSF2* intron 10 Heat shock transcription factor 2 NM_004506 Transcription
C10 2q31-q32.1 CHN1 intron 5 Chimerin 1 NM_001025201 Signal transduction
C11 8q24.13 FBXO32* intron 4 F-box protein 32 NM_058229 Protein degradation
D2 5q21.3 PJA2* 5' end Praja2, RING-H2 motif containing NM_014819 Ubiquitin ligase
D5 5q31.3 NR3C1* intron 2 Nuclear receptor subfamily 3 NM_00176 Signal transduction
D7 Xq21.1 POF1B* 5' end Premature ovarian failure NM_024921 Cytoskeleton organization
D9 8q12.3 YTHDF3 3' end YTH domain family member 3 NM_152758 Unknown
D12 6p21.3 DDR1* intron 3 Discoidin domain receptor, family member 1 NM_013993 Cell adhesion
E2 10p12.1 GPR158* intron 4 G-protein coupled receptor 158 NM_020752 Signal transduction
E6 5q31.1 SLC22A4 intron 1 Solute carrier family 22, member 4 NM_003059 Transport
E12 9q13 B4GALT1* intron 1 UDP-Gal:betaGLCNAc beta 1,4-galtosyltransferase NM_001497 Carbohydrate metabolism
G9 12q24.31 AACS 3'end Acetoacetyl-CoA synthetase NM_145248 Metabolism
H3 2q21.1 WASPIP* intron 2 Wiskott-Aldrich syndrome protein interacting protein NM_003387 Cytoskeleton organization
H4 15q21.2 SPPL2A 5' end Signal peptide peptidase-like 2A NM_032802 Protein degradation
H6 7p15-p14 TBX20 5' end T-Box 20 NM_020417 Transcription
H8 12q13 SLC38A4 5' end Solute carrier family 38, member 4 NM_018018 Transport
H12 3q27 MCCC1 intron 10 Methylcrotonoyl-Coenzyme A caboylase 1 NM_020166 Metabolism
I5 22q12.3 SYN3* intron 6 Synapsin 3 NM_003490 Neurotransmitter secretion
J1 7p12-p11.2 GRB10 intron 3 Growth factor receptor-bound protein 10 NM_00100549 Signaling
J2 1q21.2 NOTCH2NL* intron 1 Notch homolog 2 NM_203458 Signal transduction
J3 14q32.3 MARK3 intron 4 MAP-microtubule affinity regulating kinase 3 NM_002376 Kinase activity
J5 5q35.3 MXD3 intron 4 MAX dimerization protein 3 NM_031300 Transcription
J7 8q12.1 RGS20* intron 4 Regulator of G-protein 20 NM_003702 Signal transduction
E1 3q25.3 TADA3L 3' end Transcriptional adaptor 3 NM_006354 Transcription
  1. Shown are known genes located closest to each p63 ChIPed DNA sequence and the corresponding chromosome number. Also shown are the location of the p63-binding site within each gene, NCBI accession number, and gene function. Asterisks indicates those genes that were also identified by other studies.