Figure 7From: An Rb1-dependent amplification loop between Ets1 and Zeb1 is evident in thymocyte differentiation and invasive lung adenocarcinoma Zeb1 mutation eliminates Ets1 expression in differentiating embryonic thymocytes. A-G H&E sections of embryonic day 15.5 wild-type and Zeb1(−/−) embryos showing the thymus (T). Note the decrease in thymocyte number with Zeb1 mutation. (C-J) Immunostaining showing loss of expression of Ets1 with Zeb1 mutation in differentiating thymocytes. CD3 is a T-cell marker.Back to article page