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Table 1 Genes included in the TaqMan® low density human endogenous control panel

From: Identification of Importin 8 (IPO8) as the most accurate reference gene for the clinicopathological analysis of lung specimens

Gene symbol

Gene name

Function

18S

18S Ribosomal RNA

One 18S molecule makes the small subunit of the ribosome

ACTB

Beta-Actin

Cytoskeletal structural protein

B2M

Beta-2-Microglobulin

Beta-chain of major histocompatibility complex class I molecules

GAPDH

Glyceraldehyde-3-phosphate dehydrogenase

Oxidoreductase in glycolysis and gluconeogenesis

GUSB

Beta-Glucuronidase

Degradation of dermatan and keratan sulfates

HMBS

Hydroxymethylbilane synthase

Heme synthesis, porphyrin metabolism

HPRT1

Hypoxanthine phosphoribosyl transferase

Purine synthesis in salvage pathway

IPO8

Importin8

Function in nuclear protein import

PGK1

Phosphoglycerate kinase

Glycolytic enzyme

POLR2A

RNA Polymerase II

Catalyzes the RNA synthesis from DNA

PPIA

Peptidylprolyl isomerase A

Catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides, accelerating folding

RPLP0

Ribosomal large P0

Ribosome biogenesis and assembly

TBP

TATA binding protein

General RNA polymerase II transcription factor

TFRC

Transferrin receptor

Cellular uptake of iron

UBC

Ubiquitin C

Protein degradation

YWHAZ

Tyrosinmonooxygenase/Tryp-tophanmonooxygenase activation protein

Signal transduction by binding to phosphorylated serine residues on a variety of signaling molecules