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Figure 1 | BMC Molecular Biology

Figure 1

From: Regulation of poly(ADP-ribose) polymerase-1 (PARP-1) gene expression through the post-translational modification of Sp1: a nuclear target protein of PARP-1

Figure 1

Expression of PARP-1, Sp1, Sp3 and NFI in PARP-1+/+ and PARP-1-/- cells. Crude nuclear extracts (10 μg) from both PARP-1+/+ and PARP-1-/- cells were examined in Western blot using antibodies directed against PARP-1, Sp1, Sp3 and NFI. The position of the 120 kDa and 60 kDa proteins used as molecular mass markers is indicated. The asterisk indicates the position of the typical NFI complex whereas the arrowhead designates NFI complexes with a reduced electrophoretic mobility that predominated in the extract from PARP-1-/- cells. Data of one from three similar experiments are presented.

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BMC Molecular Biology

ISSN: 1471-2199

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