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Table 1 Overview of GAPDH expression by different tumor and non-tumor cell lines as a consequence of the development of a hypoxic cellular microenvironment

From: GAPDH is not regulated in human glioblastoma under hypoxic conditions

Cell line or type Origin Genetic mutations (-/+) GAPDH overexpression under hypoxia Ref. GAPDH Ref. mutations
LNCap - Human prostate adenocarcinoma cells - No mutations + [35] [27]
ATII -Rat alveolar epithelial cells - No mutations + [26] [26]
SiHA -Human spontaneous cervical cancer cells - No mutations
Wild type p53
+ [36] [37]
MBEC4 -Mouse brain capillary endothelial cells - No mutations + [38] [38]
EC - Human endothelial cells - Not determined Mutated epithelial cells are present + [5], [22], [23], [24] [39], [40] [40]
Skeletal muscles from hindlimbs of newborn white New Zealand rabbits - Rabitts skeletal muscle cells - Not determined + [41] -
Bovine articular chondrocytes -Bovine chondrocytes - Not determined - [38] -
U373 – MG -Human malignant glioma cells -Apoptosis resistant mutant P53
- Peroxisome proliferator activated receptor – γ
- PTEN mutation
- - [42], [43],
[44],
GaMG -Human malignant glioma cells - No mutations - - [34], [44]
U251 -Human malignant glioma cells -Mutated p53 – P14ARF/P16 deletion - - [43], [46]