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Table 1 List of transcripts upregulated by 16 h-leptin treatment in RINm5F cells

From: Leptin induces inflammation-related genes in RINm5F insulinoma cells

    

Signal intensities†

 
 

Gene symbol*

GenBank Accession.

UniGene

mock

leptin

Fold induction by leptin

Phosphatidate phosphohydrolase 2a

Ppap2a

AI555126

Rn.61687

0.3

2.4

8.9

Regulator of G-protein signaling 4

Rgs4

AI502324‡

Rn.11065

3.2

16.9

5.2‡

Preprotachykinin 1

Tac1

AA818532

Rn.1920

44.6

188.2

4.2

Fibrinogen, beta polypeptide

Fgb

AI059690§

Rn.11416

3.0

11.4

3.8§

Plasminogen activator, tissue-type (tPA)

Plat

AA875008

Rn.107102

2.3

7.7

3.3

Lipocalin 2

Lcn2

AI137617

Rn.11303

2.7

8.7

3.2

Pancreatitis-associated protein (PAP1)

Pap

AA998280

Rn.9727

1.9

5.5

2.9

superoxide dismutase 2 (MnSOD)

Sod2

AI029806

Rn.10488

17.1

48.3

2.8

  1. * Official gene symbol in the Rat Genome Database
  2. † Phosphoimager evaluation of filter array hybridization (relative units corrected to background and normalized to β actin
  3. ‡ Representative of four different Rgs4 cDNA clones (ratios: 5.2, 2.9, 2.8 and 2.4).
  4. § Representative of two different fibrinogen-β cDNA clones (ratios: 3.8 and 2.8).