Table 3 Number of Adenoviral DNA copies per liver determined by duplex real time PCR. This table refers to the animals depicted in Fig. 3 and in Table 2. The number of DNA copies was determined from a small weighted mass of liver and then extrapolated to the total liver mass. Data are expressed as mean ± SD
From: Genetic heterogeneity in response to adenovirus gene therapy
Adenoviral copies (× 107) / liver | ||||
|---|---|---|---|---|
Dose | N | Wag/Rij | Brown Norway | |
Ad5 Adapt Luc | 10 10 iu | 6 | 160 ± 80 | 130 ± 50 |
3.10 9 iu | 6 | 17 ± 11 | 19 ± 12 | |
Ad5 Adapt LacZ | 10 10 iu | 6 | 159 ± 50 | 161 ± 51 |
3.10 9 iu | 3 | 45 ± 12 | 28 ± 8 | |
10 9 iu | 3 | 5.2 ± 0.7 | 9.4 ± 3 | |