Effect of starvation and refeeding on the relative abundance of ACC- α mRNA molecules derived from PIA, PII, and from all promoters (total) in the liver. The relative concentration of mRNA molecules derived from PIA, PII and all ACC-α encoding messages were measured from liver biopsies. These were taken from normally fed animals (Fed), probed again after starvation (43 h, Starved) and after subsequently refeeding them for 29 h (Refed). Values were normalized relative to the mean concentrations as measured from the well fed animals, set as 100 %. Shown are the mean values (±S.E.M., n = 4). Statistical significance of differences was calculated against respective Fed samples (* P < 0.05; ** P < 0.01).