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Figure 2 | BMC Molecular Biology

Figure 2

From: PIM-1 kinase interacts with the DNA binding domain of the vitamin D receptor: a further kinase implicated in 1,25-(OH)2D3 signaling

Figure 2

Domain analysis of PIM-1 – VDR interaction. (A) Yeast cells co-transformed with PIM-1-pAD-Gate2 and VDR-Fullength-pBD-Gate2 grow directly on PPI selective medium as well as yeast cells co-transformed with PIM-1-pAD-Gate2 and DBD-pBD-Gate2. Cells co-transformed with PIM-1-pAD-Gate2 and LBD-pBD-Gate2, PIM-1-pAD-Gate2 and pBD-Gate2, pAD-Gate2 and VDR-Fullength-pBD-Gate2, pAD-Gate2 and DBD-pBD-Gate2, or pAD-Gate2 and LBD-pBD-Gate2 show no growth on PPI selective medium. (B) All combination show strong growth on medium selective for positive transformation.

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BMC Molecular Biology

ISSN: 1471-2199

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