Figure 12
MTGR1 promoter activity in various cell lines. pGL3/-499 to +52 (the shortest construct with full promoter activity) was transfected to indicated cell lines and luciferase activity was determined as described in Methods. The relative MTGR1 mRNA expression of the cell lines is also given. The promoter shows a 1 to 2.5-fold increased reporter signal in most cell lines. MEG-01, HL-60 and COS cells show both the lowest reporter signals and the lowest MTGR1 mRNAs.