Effect of mutations in PKC and calcineurin pathways and in CMK2 and PTK2 on Ste11ΔNp stimulation of reporter genes. STE11ΔN activation of FKS2 (-928 to +1)-lacZ (A), FKS2 (-706 to +1)-lacZ (B), PRM5-lacZ (C) and Δ-178 pCYC1-lacZ (D) in cell wall integrity and filamentous pathway mutants. STE11ΔN activation of FKS2 (-928 to +1)-lacZ (E), FKS2 (-706 to +1)-lacZ (F), PRM5-lacZ (G) and Δ-178 pCYC1-lacZ (H) in calcineurin pathway mutants. Data were expressed as mean ± SE of at least three independent experiments. Statistical significance was computed by the unpaired Student's t test. *p < 0.05, **p < 0.01.