SWI/SNF regulates the alternative processing of a specific subset of pre-mRNAs in Drosophila melanogaster

BMC Molecular Biology

Table 1 Gene ontology analysis of genes affected by depletion of SWI/SNF in S2 cells

Genes with pre-mRNA processing affected
GO ID	Term	Log (odds ratio)	p
0009790	embryo development	2.33	0.0088
0009887	organ morphogenesis	2.75	0.0010
0048513	organ development	2.11	0.0032
0001745	compound eye morphogenesis	3.14	0.0059
0007601	visual perception	3.60	0.0098
0050953	sensory perception of light stimulus	3.59	0.0098
0051252	regulation of RNA metabolic process	2.06	0.0098
Genes with promoter usage affected
GO ID	Term	Log (odds ratio)	p
0022402	cell cycle process	2.76	0.0045
0000279	M phase	3.00	0.0034
0000022	mitotic spindle elongation	4.51	0.0021
0007052	mitotic spindle organization	3.33	0.0079
0000226	microtubule cytoskeleton organization	3.92	< 0.0001
0048513	organ development	2.25	0.0043
0035220	wing disc development	3.22	0.0043
0048190	wing disc dorsal/ventral pattern formation	5.01	0.0011
0009165	nucleotide biosynthetic process	3.50	0.0060
0003735	structural constituent of ribosome	3.16	0.0098
0006996	organelle organization	2.24	0.0043
0065008	regulation of biological quality	2.37	0.0096

The table shows the results from GO-enrichment analysis for two separate groups of genes, as indicated. The table shows terms that include more than two hits, that show a log (odds ratio) > 2 (odds ratio > 7.3) and p < 0.01 (hypergeometric test).

ISSN: 1471-2199