Increased complexity of Tmem16a/Anoctamin 1 transcript alternative splicing

O'Driscoll, Kate E; Pipe, Rachel A; Britton, Fiona C

doi:10.1186/1471-2199-12-35

BMC Molecular Biology

Table 1 Genomic Organization of Tmem16a

From: Increased complexity of Tmem16a/Anoctamin 1 transcript alternative splicing

Human		Mouse
Exon number	Exon size (bp)	Exon number	Exon size (bp)	3' Acceptor and 5' Donor splice site sequences	Intron size (bp)
1	413	1	119	CAGGTG gt agga	~59,580
		1b	146	ttgcag ACGCCA---------------------GGCACG gt gagt	8,958
2	333	2	333	tcacag TTGCTG---------------------GAGGAT gt gagt	12,229
3	99	3	99	ctctag ACCAAA---------------------AAGAAG gt gagt	1,264
4	152	4	152	ccacag GTGTAC----------------------ACACCT gt gagt	1,340
5	55	5	55	ctgcag ATTCGA----------------------ACAATA gt gagt	3,649
6	52	6	52	ccctag GTCTAT---------------------GCATGG gt aagg	1,862
6b	66	6b	66	aaacag GGCAAG--------------------AATACG gt aaga	495
7	56	7	56	ttaaag GTATCA----------------------CACGAT gt aagt	3,274
8	42	8	42	tcacag GGGGAC--------------------AGGAAA gt aagt	6,143
9	65	9	65	ccccag CTCCTG----------------------GGTCAG gt aagt	1,290
10	135	10	135	gcatag GAAATA---------------------CCCCAG gt aggc	3,318
11	161	11	161	ttacag TATGGA----------------------TCTGGG gt aagt	11,845
12	83	12	83	ctacag CTGCCA---------------------GAGGAG gt gagt	2,181
13	12	13	12	ccgcag GAAGCT---------------------GTCAAG gt ttga	161
		13b	120	ttccag CACCTT----------------------CAGAGG gt cagt	273
14	72	14	72	tctcag GATCAT---------------------AAAGAG gt acag	2,874
	78	15	78	cctcag AAGTGC----------------------AAATTG gt actt	972
16	75	16	75	ttgcag ACCGAC----------------------TTCATG gt aagt	3,034
17	202	17	202	ctgcag ATCGCA----------------------AGATTG gt gagt	167
18	112	18	112	cctcag AGGTCC---------------------AGGCCG gt agga	434
19	58	19	58	tcccag GTTTGT---------------------GAGGAG gt aata	1,892
20	101	20	101	ctacag TGTGCC----------------------CATCCC gt gagt	786
21	146	21	146	ctgcag GAAGAT---------------------AAATGA gt gagt	4,324
22	153	22	153	ctgcag TCATTC-----------------------ACATCG gt aagt	6,207
23	53	23	53	ctctag GCATCT-----------------------ATTAAT gt aagt	1,554
24	185	24	185	tggcag GCCTTT----------------------CTGCAG gt acta	2,635
25	106	25	106	ttgcag GTATAA-----------------------TTCCAG gt atgt	2,435
26	1809	26	1621	ctgcag AACCTG

Intron size refers to the intron following the exon listed in each row.

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ISSN: 1471-2199

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