Figure 2
From: High-resolution melting curve analysis for rapid detection of mutations in a Medaka TILLING library
ENU-induced mutations identified by TILLING in the Oryzias latipes atr gene (OlATR). (A) Genome organization and protein structure of the medaka atr gene. Conventions are as in Fig. 1. The ATRIP binding domain, HEAT domain, FAT domain, PI3-kinase domain (kinase), and FATC domain are shown in the protein. High-resolution melting curves (B, D, F, H) and subtraction plots (C, E, G, I) of identified ENU-induced mutations in exons 12-13, 19-21, 24, and 45 of the atr gene are shown.