Figure 6
From: TAF6δ orchestrates an apoptotic transcriptome profile and interacts functionally with p53
Evidence for transcriptional crosstalk between endogenous TAF6δ and p53. (A) Venn diagram illustrating the partitioning of previously characterized p53-regulated genes [5] into TAF6α and TAF6δ dependent classes. (B) Examples of TAF6δ but not TAF6α dependent p53 target genes. Log base 2 fold changes in gene expression are shown graphically. Error bars show the standard deviations over three independent experiments and gene symbols are shown at the bottom. (C) Examples of TAF6α but not TAF6δ dependent p53 target genes (as in panel B). (D) Examples of TAF6α and TAF6δ dependent p53 target genes (as in panel B). (E) Previously characterized TAF6δ target genes [5] partition into p53 dependent and independent genes as illustrated with Venn diagrams. (F) Examples of p53 dependent and independent TAF6δ target genes (as in panel B).