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Figure 2 | BMC Molecular Biology

Figure 2

From: Natural antisense transcript of natriuretic peptide precursor A (NPPA): structural organization and modulation of NPPA expression

Figure 2

Expression analysis of Nppa and Nppa-as in mouse tissues. (A) Nppa is expressed in all tissues that were tested and Nppa-as is expressed in the brain. Nppa was amplified using primers mNppa-F and mNppa-R, Nppa-as was detected using primers mNppa-asF and mNppa-asR (indicated by arrows marked F, R, asF and asR on Figure 2B, respectively). (B) Genomic organization of NPPA locus in mouse and human. Arrowheads indicate the direction of transcription. Conservation profile of the human sequence, based on the UCSC vertebrate conservation track is shown below. Conservation is detected in the coding region (depicted as black boxes), promoter area and 3' terminus of NPPA gene, but not in the NPPA-AS exons that are located in introns or downstream of the NPPA gene.

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BMC Molecular Biology

ISSN: 1471-2199

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