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Table 1 Differential expression of candidate reference genes in HNSCC tissue and matched normal mucosa (46 patients)

From: Reference gene selection for head and neck squamous cell carcinoma gene expression studies

 

Normal tissue

HNSCC tissue

 

Gene

Median

Min

Max

Median

Min

Max

P value

ACT

2.302

0.029

8.642

1.466

0.151

27.537

<0.001

ALAS

2.407

0.065

8.106

2.426

0.083

14.561

0.623

B2M

1.384

0.062

7.521

2.148

0.112

11.168

0.038

GADPH

2.087

0.368

5.070

2.948

0.145

17.192

<0.001

HMBS

1.944

0.045

5.278

1.989

0.238

10.071

0.043

HPRT

1.365

0.037

3.708

2.316

0.102

18.128

<0.001

KALPHA

1.590

0.020

5.908

3.174

0.095

17.656

<0.001

RPS18

2.207

0.258

12.132

2.690

0.093

21.544

0.039

RPL27

2.112

0.022

8.797

2.027

0.228

23.993

0.140

RPS29

2.875

0.090

22.910

2.362

0.020

18.233

0.015

SHAD

1.612

0.064

4.218

1.723

0.074

13.097

0.939

TBP

1.466

0.151

27.537

1.645

0.224

7.052

0.010

  1. Median, minimum and maximum relative gene expression ratios of 12 reference genes in HNSCC tissue versus normal tissue are presented with corresponding p-values (Wilcoxon test for paired data). Rescaled values provided by qBase software are presented.