Figure 2

Multiple euchromatic histone modifiers promote gene silencing by redundant mechanisms. (A) Analysis of telomeric silencing at 23, 30, and 37°C. (B-G) Single, double and triple mutants of the indicated genes involved in chromatin modification were analyzed as in Figure 1. dot1Δ strains have a partial silencing defect and are 5-FOA sensitive at 30°C. Cells were spotted at 37°C to partially restore silencing and identify mutants that enhance the partial silencing defect of dot1Δ. Each section represents a different experimental panel.