Figure 6

A model of co-transcription, alternative splicing and exonization of TE sequences in the generation of the T1 (A), T2 (B) and T1–T2 chimeric (C) transcripts. The ordered exon assemblage shown at the top of the scheme is as depicted in Figure 5A. Primary transcript A (Pri-A) is proposed for the generation of the T2 transcripts, and the transcription read-through primary transcripts Pri-B1 and -B2 are proposed for the generation of the T1 and T1–T2 chimeric transcripts, respectively, as explained in the text. In the figure, only transcripts that exemplify representative exon usages are shown. Exons 4a and 4b and exons 6a and 6b carry the T2 and T1 coding sequences, respectively, as indicated. Since chimeric sequences in panel (C) were derived by RT-PCR, only the derived exon sequences are shown. See also Figure 5 legend for an explanation of the symbols and colour code used.