Skip to main content
Figure 6 | BMC Molecular Biology

Figure 6

From: Evidence of a tick RNAi pathway by comparative genomics and reverse genetics screen of targets with known loss-of-function phenotypes in Drosophila

Figure 6

Cell culture knockdown. (a). Growth and viability RNAi phenotypes expressed as inverse z-scores of genes involved in ribosome and protein synthesis (TC5762, TC9037, TC12306, TC12393), encoding proteasome components and participating in ubiquitinylation (TC6372, TC9852, TC10417, TC13930), and having DNA binding functions (TC6116, TC12182). A positive z-score indicates reduced cell growth and viability. (b). Effect of dsRNA-induced knockdown on RNAi targets measured by quantitative RT-PCR and presented as % of gene expression levels relative to the housekeeping gene.

Back to article page