Fig. 2From: Identification of G-quadruplex structures that possess transcriptional regulating functions in the Dele and Cdc6 CpG islandsReporter assay for evaluation of the promoter activities of Cdc6, Dele-F, and Dele-R G4 DNAs. The G4-forming sequences were cloned into the pGL4.10 vector not containing any promoter. Black bars represent the wild-types and white bars represent the mutant-types. Luciferase activities relative to the pGL4.10 vector are shown (mean ± SD, n = 3). Wild- and mutant-types samples t-test differences: ***P < 0.0001Back to article page