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Most Accessed Articles: BMC Molecular Biologyhttp://bmcmolbiol.biomedcentral.comMost Accessed Articles: BMC Molecular BiologyThe RIN: an RNA integrity number for assigning integrity values to RNA measurements integrity of RNA molecules is of paramount importance for experiments that try to reflect the snapshot of gene expression at the moment of RNA extraction. Until recently, there has been no reliable standar...Tue, 31 Jan 2006 00:00:00 GMT Schroeder, Odilo Mueller, Susanne Stocker, Ruediger Salowsky, Michael Leiber, Marcus Gassmann, Samar Lightfoot, Wolfram Menzel, Martin Granzow and Thomas Ragg2006-01-31T00:00:00ZEvaluation of putative reference genes for gene expression normalization in soybean by quantitative real-time RT-PCR quantitative reverse transcription PCR (RT-qPCR) data needs to be normalized for its proper interpretation. Housekeeping genes are routinely employed for this purpose, but their expression level cann...Mon, 28 Sep 2009 00:00:00 GMT Hu, Chengming Fan, Hongyu Li, Qingzhu Zhang and Yong-Fu Fu2009-09-28T00:00:00ZSelection of housekeeping genes for gene expression studies in human reticulocytes using real-time PCR genes, which are often referred to as housekeeping genes, are frequently used to normalise mRNA levels between different samples. However, the expression level of these genes may vary among tissues or ...Fri, 06 Oct 2006 00:00:00 GMT Silver, Steve Best, Jie Jiang and Swee Lay Thein2006-10-06T00:00:00ZCruciform structures are a common DNA feature important for regulating biological processes cruciforms play an important role in the regulation of natural processes involving DNA. These structures are formed by inverted repeats, and their stability is enhanced by DNA supercoiling. Cruciform struc...Fri, 05 Aug 2011 00:00:00 GMTáclav Brázda, Rob C Laister, Eva B Jagelská and Cheryl Arrowsmith2011-08-05T00:00:00ZCharacterization of housekeeping genes in zebrafish: male-female differences and effects of tissue type, developmental stage and chemical treatment using the zebrafish model has experienced a rapid growth in recent years. Although real-time reverse transcription PCR (QPCR), normalized to an internal reference ("housekeeping") gene, is a frequentl...Wed, 12 Nov 2008 00:00:00 GMT T McCurley and Gloria V Callard2008-11-12T00:00:00Z

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Aims and scope

BMC Molecular Biology is an open access journal publishing original peer-reviewed research articles in all aspects of DNA and RNA in a cellular context, encompassing investigations of chromatin, replication, recombination, mutation, repair, transcription, translation and RNA processing and function.

Section Editors

  • Jean-Francois Beaulieu, Universite de Sherbrooke
  • Frances V Fuller-Pace, University of Dundee
  • Stuart MacNeill, University of St. Andrews
  • Christian Zwieb, University of Texas Health Science Center at San Antonio

Executive Editor

  • Tim Sands, BioMed Central