Fig. 4From: Strong preference of BRCA1 protein to topologically constrained non-B DNA structuresAFM images of DNA and BRCA1-L/DNA complexes. The first column shows the representative AFM images of different DNAs A linearized pBluescript, C superhelical pBluescript, E pCFNO containing cruciform structures (arrow), G pTA50 containing a triplex structure (arrow) and I pCMYC containing a quadruplex structure (arrow). In the second column B, D, F, H, J, the complexes of BRCA1-L with these plasmid DNAs are shown by arrows and are visible as white circular spots on the DNA strandsBack to article page