Figure 3From: Hepatoma derived growth factor binds DNA through the N-terminal PWWP domainHDGF requires a minimal 37 bp DNA sequence for binding. Sequential 3'(A) or 5' (B) end serial deleted (3–5 bp) probes were synthesized and used in an EMSA to identify a minimum DNA binding sequence. The bottom schematic diagram elucidates the locations of deleted probes relative to the 80 bp long probe. A 37 bp probe was identified as the minimal DNA binding sequence.Back to article page