Figure 6From: A potential role of alternative splicing in the regulation of the transcriptional activity of human GLI2 in gonadal tissuesAlternative splicing in the 5' end of GLI2 mRNA. Exons corresponding to cloned and/or sequenced splice variants are marked by bold lines. Exon and intron splice junction sequences are designated by upper and lower case letters, respectively. Alternatively spliced forms I-III arising via exon skipping and different exon 6–7 junction usage (described in this study) are compared with the previously published sequence (Type IV) [32]. For each alternatively spliced form, GenBank accession number is shown on the right. Translation of these sequences initiated from ATG codon located in exon 2 (METSA) terminates with premature termination codons (PTC). Location of initiator codon described previously [32] is shown in exon 7 (M). Location of the SUFU binding site (SYGH) in exon 6 is shown.Back to article page