https://bmcmolbiol.biomedcentral.com/articles/10.1186/s12867-016-0055-y
https://bmcmolbiol.biomedcentral.com/articles/10.1186/s12867-016-0059-7
https://bmcmolbiol.biomedcentral.com/articles/10.1186/s12867-016-0060-1