https://bmcmolbiol.biomedcentral.com/articles/10.1186/s12867-015-0054-4 https://bmcmolbiol.biomedcentral.com/articles/10.1186/s12867-016-0058-8 https://bmcmolbiol.biomedcentral.com/articles/10.1186/s12867-016-0057-9 https://bmcmolbiol.biomedcentral.com/articles/10.1186/s12867-016-0056-x