https://bmcmolbiol.biomedcentral.com/articles/10.1186/s12867-015-0043-7
https://bmcmolbiol.biomedcentral.com/articles/10.1186/s12867-015-0045-5
https://bmcmolbiol.biomedcentral.com/articles/10.1186/s12867-015-0044-6