https://bmcmolbiol.biomedcentral.com/articles/10.1186/1471-2199-7-21
https://bmcmolbiol.biomedcentral.com/articles/10.1186/1471-2199-7-22
https://bmcmolbiol.biomedcentral.com/articles/10.1186/1471-2199-7-23
https://bmcmolbiol.biomedcentral.com/articles/10.1186/1471-2199-7-24