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Fig. 2 | BMC Molecular Biology

Fig. 2

From: The effect of BACE1-AS on β-amyloid generation by regulating BACE1 mRNA expression

Fig. 2

Exogenous Aβ1-42 induces BACE1-AS and BACE1 expression and Aβ generation in the brains of C57BL/6J mice. Three days after injection of Aβ1-42 into the CA1 region of left side hippocampus of the mouse using experimental group using stereotactic technique, the expression of BACEl-AS and BACEl mRNA increased in the hippocampus on the injected side (*P < 0. 05 vs. control group) (a), and the content of Aβ1-40 raised compared with the control group (*P < 0.05 vs. control group) (b)

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