Fig. 1

Expression features of miR-325-3p in MI mice. a The expression profiles of miRNAs in MI mice. Twenty miRNAs with the greatest changes in MI mice are shown. The miRNAs that have high expression or low expression are colored red and blue. b The expression of the downregulated miRNAs in MI tissues were analyzed by qRT-PCR analysis. *P < 0.05, **P < 0.01, ***P < 0.001 compared to the mice that received the sham operation. c The influence of agomiR-325-3p or antagomiR-325-3p on the expression of miR-325-3p in MI mice. **P < 0.01 compared to MI mice treated with agomiR-control. MI, myocardial infarction; agomiR-325-3p, miR-325-3p agomir; antagomiR-325-3p, miR-325-3p antagomir; agomiR-control, scrambled agomir or antagomir control