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Table 4 GO annotation for the down-regulated DEGs in the PPI network

From: MEF2A alters the proliferation, inflammation-related gene expression profiles and its silencing induces cellular senescence in human coronary endothelial cells

Pathway ID Pathway description Count in gene set False discovery rate (FDR)
Biological process (GO)
 GO:0050793 Regulation of developmental process 84 0.000902
 GO:0048387 Negative regulation of retinoic acid receptor signaling pathway 8 0.00358
 GO:0051239 Regulation of multicellular organismal process 88 0.00358
 GO:0045595 Regulation of cell differentiation 60 0.00957
 GO:0050995 Negative regulation of lipid catabolic process 6 0.00957
Cellular component (GO)
 GO:0005615 Extracellular space 66 8.23e−07
 GO:0005576 Extracellular region 145 0.000952
 GO:0071944 Cell periphery 143 0.0129
 GO:0005886 Plasma membrane 139 0.0259
KEGG pathways
 05146 Amoebiasis 10 0.0173
 05150 Staphylococcus aureus infection 7 0.0173
 05164 Influenza A 14 0.0173
 05323 Rheumatoid arthritis 9 0.0173
 04740 Olfactory transduction 21 0.0413