Table 4 GO annotation for the down-regulated DEGs in the PPI network
Pathway ID | Pathway description | Count in gene set | False discovery rate (FDR) |
|---|---|---|---|
Biological process (GO) | |||
GO:0050793 | Regulation of developmental process | 84 | 0.000902 |
GO:0048387 | Negative regulation of retinoic acid receptor signaling pathway | 8 | 0.00358 |
GO:0051239 | Regulation of multicellular organismal process | 88 | 0.00358 |
GO:0045595 | Regulation of cell differentiation | 60 | 0.00957 |
GO:0050995 | Negative regulation of lipid catabolic process | 6 | 0.00957 |
Cellular component (GO) | |||
GO:0005615 | Extracellular space | 66 | 8.23e−07 |
GO:0005576 | Extracellular region | 145 | 0.000952 |
GO:0071944 | Cell periphery | 143 | 0.0129 |
GO:0005886 | Plasma membrane | 139 | 0.0259 |
KEGG pathways | |||
05146 | Amoebiasis | 10 | 0.0173 |
05150 | Staphylococcus aureus infection | 7 | 0.0173 |
05164 | Influenza A | 14 | 0.0173 |
05323 | Rheumatoid arthritis | 9 | 0.0173 |
04740 | Olfactory transduction | 21 | 0.0413 |