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Table 1 GO annotation for the down-regulated DEGs with potential MEF2A binding sites in the proximal promoter

From: MEF2A alters the proliferation, inflammation-related gene expression profiles and its silencing induces cellular senescence in human coronary endothelial cells

Category Term Count (%) p-value Fold enrichment
GAD_DISEASE_CLASS Reproduction 8 (13.33) 0.03294 2.51
GAD_DISEASE_CLASS Cardiovascular 21 (35) 0.03316 1.48
UP_KEYWORDS Secreted 18 (30) 0.00002 3.14
UP_KEYWORDS Disulfide bond 21 (35) 0.00097 2.10
UP_KEYWORDS Signal 23 (38.33) 0.00181 1.90
UP_KEYWORDS Glycoprotein 22 (36.67) 0.01248 1.66
UP_KEYWORDS Cell junction 7 (11.67) 0.01257 3.56
UP_KEYWORDS Cell membrane 16 (26.67) 0.03143 1.73
UP_KEYWORDS Citrullination 3 (5) 0.03161 10.61
UP_KEYWORDS Actin-binding 4 (6.67) 0.04397 5.01
UP_KEYWORDS Thick filament 2 (3.33) 0.04765 40.35
UP_SEQ_FEATURE Signal peptide 23 (38.33) 0.00012 2.30
UP_SEQ_FEATURE Disulfide bond 19 (31.67) 0.00132 2.18
UP_SEQ_FEATURE Zinc finger region:B box-type 3 (5) 0.01710 14.75
UP_SEQ_FEATURE Glycosylation site:N-linked (GlcNAc.) 20 (33.33) 0.03095 1.58
UP_SEQ_FEATURE Domain:B30.2/SPRY 3 (5) 0.03312 10.34