Table 6 Genes regulated in the domoic acid (DA) induced grazer treatments that are involved or suggested to be involved in the biosynthesis of DA
| Domoic acid | |||||
|---|---|---|---|---|---|
| Accession number | Mean FC | Adjusted P value | Gene name | Description |
Enzyme EC: |
| In the methylerythritol phosphate metabolic pathway (MEP) to geranyl pyrophosphate (GPP) | |||||
| PSN0016235 | 1.88 | < 0.001 | Dxr | 1-Deoxy-d-xylulose 5-phosphate reductoisomerase | 1.1.1.267 |
| PSN0004050 | 1.82 | < 0.001 | ispH | 4-Hydroxy-3-methylbut-2-enyl diphosphate reductase | 1.17.1.2 |
| PSN0005356 | 1.61 | 0.043 | ispG | 4-Hydroxy-3-methylbut-2-en-1-yl diphosphate synthase | 1.17.7.1 |
| PSN0002600 | 1.60 | < 0.001 | ispD | 2-C-Methyl-d-erythritol 4-phosphate cytidylyltransferase, chloroplastic | 2.7.7.60 |
| PSN0023754 | 1.60 | 0.013 | ispE | 4-Diphosphocytidyl-2-C-methyl-d-erythritol kinase | 2.7.1.148 |
| In the synthesis from MEP to GPP and l-glutamate towards domoic acid | |||||
| PSN0015669 | 12.23 | < 0.001 | DabB | Hypothetical protein | NA |
| PSN0029114 + PSN002498 | 11.23 | < 0.001 | DabC | Dioxygenase | NA |
| PSN0007588 | 9.41 | < 0.001 | DabA | N-prenyltransferase | NA |
| PSN0005772 | 2.83 | <0.001 | idi1-2 | Isopentenyl-diphosphate Delta-isomerase | 5.3.3.2 |
| PSN0020364 | 2.83 | < 0.001 | DabD | Cytochrome P450 | NA |
| Proline metabolism | |||||
| PSN0000830 | 1.67 | < 0.001 | P4HA | Prolyl 4-hydroxylase | 1.14.11.2 |
| PSN0001687 | 1.62 | 0.002 | NA | Ornithine cyclodeaminase | 4.3.1.12 |
