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Fig. 3 | BMC Molecular Biology

Fig. 3

From: Transcriptomic responses to grazing reveal the metabolic pathway leading to the biosynthesis of domoic acid and highlight different defense strategies in diatoms

Fig. 3

Illustration of the major metabolic pathways for the biosynthesis of domoic acid (DA). The precursor of the C10 isoprenoid can either arise via the mevalonate (MEV) pathway that is located in the cytosol and/or an alternative route in the plastid, the methyl-erythritol phosphate metabolic (MEP) pathway. The tricarboxylic acid is proposedly derived from l-glutamate. The green arrow indicates where genes are upregulated when Pseudo-nitzschia is triggered to produce DA, the assigned enzymes are highlighted bold green, number of replicates = 3. Mean fold change (FC) and adjusted P values as well EC numbers for the enzymes and are given in Table 6

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