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Table 5 Biological processes related to predicted targets genes

From: MiRNAs differentially expressed in skeletal muscle of animals with divergent estimated breeding values for beef tenderness

IDa Score Focus molecules Top diseases and functions
1 50 35 Cancer, organismal injury and abnormalities, reproductive system disease
2 42 32 Post-translational modification, cell morphology, cellular movement
3 37 30 Carbohydrate metabolism, small molecule biochemistry, hereditary disorder
4 37 30 Post-translational modification, dermatological diseases and conditions, inflammatory disease
5 37 31 Nucleic acid metabolism, small molecule biochemistry, vitamin and mineral metabolism
6 37 30 Cell-to-cell signaling and interaction, nervous system development and function, cell cycle
7 35 29 Developmental disorder, hereditary disorder, neurological disease
8 35 29 Cellular function and maintenance, lipid metabolism, small molecule biochemistry
9 35 29 Cell-to-cell signaling and interaction, carbohydrate metabolism, lipid metabolism
10 33 28 Lipid metabolism, small molecule biochemistry, molecular transport
11 31 27 Cellular development, cellular growth and proliferation, developmental disorder
12 31 27 Post-translational modification, nervous system development and function, tissue morphology
13 29 26 Organismal development, cell signaling, post-translational modification
14 29 26 Connective tissue disorders, immunological disease, inflammatory disease
15 29 26 Cell death and survival, embryonic development, nervous system development and function
16 27 25 Cellular assembly and organization, cellular function and maintenance, protein synthesis
17 27 25 Cellular movement, nervous system development and function, hereditary disorder
18 26 24 Cell signaling, tissue morphology, embryonic development
19 26 24 Gene expression, amino acid metabolism, small molecule biochemistry
20 26 24 Gene expression, cell signaling, cardiovascular system development and function
21 26 24 Cardiovascular disease, organismal injury and abnormalities, developmental disorder
22 26 24 Glutathione depletion in liver, liver fibrosis, amino acid metabolism
23 25 24 Cell-to-cell signaling and interaction, nervous system development and function, molecular transport
24 25 26 Cell morphology, post-translational modification, cellular assembly and organization
25 24 23 Behavior, organ morphology, reproductive system development and function
  1. aID represents the number of identified network, Score represents the number of genes on the network and focus molecules correspond of the number of target genes