Table 1 MAR/SARs predicted within the AF9 gene by using MRS
Predicted MAR/SAR | AWWRTAANNWWGNNNC (16Â bp) | Nucleotide position | AATAAYAA (8Â bp) | Nucleotide position | Distance (bp) | Location in exon/intron |
|---|---|---|---|---|---|---|
1 | ATAATAATAAAAGCCC (C) | 916–931 | AATAATAA (C) AATAATAA (C) | 915–922 918–925 | Overlap Overlap | Intron 1 |
2 | ATAGTAAGGATGGCTG (W) | 5636–5651 | AATAATAA (W) | 5694–5701 | 42 | Intron 2 |
3 | AAAATAACAAAGGAAG (W) | 10,555–10,570 | AATAACAA (W) | 10,561–10,568 | Overlap | Intron 2 |
4 | AATATTATTATGGGTC (W) | 26,366–26,381 | AATAATAA (W) | 26,420–26,427 | 38 | Intron 2 |
5 | AAAGTAAACTGGAAAC (C) | 47,851–47,866 | AATAACAA (W) | 47,627–47,634 | − 216 | Intron 2 |
6 | AAAATAATAATAATAC (W) | 56,224–56,239 | AATAATAA (W) AATAATAA (W) | 56,227–56,234 56,230–56,237 | Overlap Overlap | Intron 2 |
7 | AAAATCATCTTGGGAC (W) | 94,045–94,060 | AATAACAA (W) | 93,895–93,902 | − 142 | Intron 2 |
8 | AAAATAATAAAAACCC (C) | 108,633–108,648 | AATAATAA (C) | 108,635–108,642 | Overlap | Intron 2 |
9-1 | ATAATAACATTTTACC (C) | 112,369–112,384 | AATAATAA (C) | 112,368–112,375 | Overlap | Intron 2 |
9-2 | AAAATAATAATTGTAC (C) | 113,269–113,284 | AATAATAA (C) | 113,271–113,278 | Overlap | Intron 2 |
10 | ATTGGAATGTAGAAAC (W) | 117,722–117,737 | AATAACAA (W) | 117,606–117,613 | − 108 | Intron 2 |
11-1 | AATATAATCTAATTGC (W) | 128,593–128,608 | AATAACAA (C) | 128,355–128,362 | − 230 | Intron 2 |
11-2 | AAAATAAGTTTCCAGC (W) | 129,838–129,853 | AATAACAA (C) AATAATAA (C) | 129,941–129,948 129,980–129,987 | 87 126 | Intron 2 |
12 | ATAATAATAAAATCAC (W) | 136,176–136,191 | AATAATAA (W) | 136,182–136,189 | Overlap | Intron 2 |
13 | AATATAATGAATATCC (C) | 139,927–139,942 | AATAATAA (C) AATAATAA (C) AATAATAA (C) AATAATAA (C) | 139,902–139,909 139,905–139,912 139,908–139,915 139,911–139,918 | − 17 − 14 − 11 − 8 | Intron 2 |
14 | TTTATAAACTTGTTTC (C) | 151,672–151,687 | AATAATAA (W) | 151,857–151,864 | 169 | Intron 2 |
15 | AAAATAAAAAAGAGCT (C) | 158,541–158,556 | AATAATAA (W) | 158,593–158,600 | 46 | Intron 2 |
16 | AAAATAATAAATACGC (W) | 170,523–170,538 | AATAATAA (W) AATAACAA (W) | 170,529–170,536 170,619–170,626 | Overlap 80 | Intron 3a |
17-1 | ATAATAAATATGAATA (W) | 178,638–178,653 | AATAATAA (W) | 178,634–178,641 | Overlap | Intron 3b |
17-2 | AAAAGAACTAAGGTAC (W) | 179,378–179,393 | AATAATAA (W) | 179,140–179,147 | − 230 | Intron 3b |
18 | AAGGTAAATTAGCAGC (W) ATAATAATAATGTTCT (C) ATAATAATGTTCTACC (C) | 182,936–182,951 183,171–183,186 183,174–183,189 | AATAATAA (C) | 183,173–183,180 | 221 Overlap Overlap | Intron 3b |
19 | ATTATAAGAAAAATTC (W) ATAATAAAAATGTTAT (C) ATAATGATCAAGTACC (C) | 191,065–191,080 191,076–191,091 191,548–191,563 | AATAATAA (W) | 191,323–191,330 | 242 231 − 217 | Intron 3b |
20-1 | AAAATAAGAAAACATC (W) AATATAATTATGCTAA (W) | 194,333–194,348 194,753–194,768 | AATAATAA (W) | 194,511–194,518 | 162 − 234 | Intron 3b |
20-2 | AATATAAAATTGCAAG (W) | 195,275–195,290 | AATAATAA (C) | 195,198–195,205 | − 69 | Intron 3b |
21 | AAAATAATAAAGCCAT (W) | 200,768–200,783 | AATAATAA (W) | 200,774–200,781 | Overlap | Intron 3b |
22-1 | ATAATAATAATAATAC (W) | 215,365–215,380 | AATAATAA (W) AATAATAA (W) AATAATAA (W) | 215,368–215,375 215,371–215,378 215,374–215,381 | Overlap Overlap Overlap | Intron 4 |
22-2 | AAAATAAAACTGACTC (C) ATAATTACATAGACAC (W) | 215,781–215,796 216,113–216,128 | AATAACAA (C) | 215,941–215,948 | 144 − 164 | Intron 4 |
23 | ATAATAATAATGAAAG (C) | 227,849–227,864 | AATAATAA (C) AATAATAA (C) | 227,848–227,855 227,851–227,858 | Overlap Overlap | Intron 4 |
24-1 | ATAATAAGTTATAGGC (W) | 236,299–236,314 | AATAATAA (W) AATAATAA (C) | 236,308–236,315 236,343–236,350 | Overlap 28 | Intron 4 |
24-2 | AAAATAACAAAATGTC (W) AATGTAAGCAATATCC (W) | 237,605–237,620 237,817–237,832 | AATAACAA (W) | 237,611–237,618 | Overlap − 198 | Intron 4 |
24-3 | AATGTAAGCAATATCC (W) AAAGTATTGTAGACCC (C) AAAATAATAAAGGGGT (W) | 237,817–237,832 237,983–237,998 237,995–238,010 | AATAATAA (W) | 238,001–238,008 | 168 2 Overlap | Intron 4 |
24-4 | TATATAATAAAGTGAC (C) | 238,794–238,809 | AATAATAA (W) | 239,050–239,057 | 240 | Intron 4 |
25-1 | ATAATAATGAAGAAAG (C) | 246,610–246,625 | AATAATAA (C) | 246,588–246,595 | − 14 | Intron 4 |
25-2 | ATTGTAATATTGATTG (C) AATATTACAATGAATC (W) TTTATAAATTAGGGAC (W) | 247,587–247,602 247,582–247,597 247,758–247,773 | AATAACAA (C) | 247,561–247,568 | − 18 − 13 − 189 | Intron 4 |
26-1 | AAAGTAAATAAAAAAC (W) | 251,265–251,280 | AATAATAA (C) | 251,344–251,351 | 63 | Intron 4 |
26-2 | AATGAAAGGAAGAGCC (W) ATAATAATAATGAAAA (C) | 252,636–252,651 252,891–252,906 | AATAATAA (C) | 252,893–252,900 | 241 Overlap | Intron 4 |
27 | ATAATAAACTACCATC (W) ATAATAATAAACTACC (W) AAAATAAACTATTTTC (C) | 262,931–262,946 262,934–262,949 263,198–263,213 | AATAATAA (W) | 262,940–262,947 | Overlap Overlap − 250 | Intron 7 |
28-1 | AATATAATCTTGAACG (C) | 265,612–265,627 | AATAATAA (C) | 265,768–265,775 | 140 | Intron 7 |
28-2 | AAAATAAAAATATGCC (C) AATAAAAATATGCCCC (C) ATAATAAGGCTGGGAC (C) ATTTTAAGAATGAGTC (W) AAGATAAATTAGGTCC (C) | 266,963–266,978 266,965–266,980 267,134–267,149 267,205–267,220 267,317–267,332 | AATAATAA (C) | 267,133–267,140 | 154 152 Overlap − 64 − 176 | Intron 7 |
28-3 | AAGATAAATTAGGTCC (C) | 267,317–267,332 | AATAATAA (C) | 267,569–267,576 | 236 | Intron 7 |
29 | AAAAAAAAATTGTAAC (W) | 273,593–273,608 | AATAACAA (W) | 273,528–273,535 | − 57 | Intron 9 |