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Fig. 1 | BMC Molecular Biology

Fig. 1

From: Identification of G-quadruplex structures that possess transcriptional regulating functions in the Dele and Cdc6 CpG islands

Fig. 1

Luciferase reporter assay for evaluation of the enhancer activities of G4 DNA sequences. The G4-forming sequences were cloned into the pGL4.23 vector containing minimal promoter. Black bars represent the wild-types and white bars represent the mutant-types. Luciferase activities relative to the pGL4.23 vector are shown (mean ± SD, n = 3). Wild- and mutant-types samples t-test differences: *P < 0.01, **P < 0.001, ***P < 0.0001

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