TY - JOUR AU - Croft, Laura V. AU - Ashton, Nicholas W. AU - Paquet, Nicolas AU - Bolderson, Emma AU - O’Byrne, Kenneth J. AU - Richard, Derek J. PY - 2017 DA - 2017/05/15 TI - hSSB1 associates with and promotes stability of the BLM helicase JO - BMC Molecular Biology SP - 13 VL - 18 IS - 1 AB - Maintenance of genome stability is critical in human cells. Mutations in or loss of genome stability pathways can lead to a number of pathologies including cancer. hSSB1 is a critical DNA repair protein functioning in the repair and signalling of stalled DNA replication forks, double strand DNA breaks and oxidised DNA lesions. The BLM helicase is central to the repair of both collapsed DNA replication forks and double strand DNA breaks by homologous recombination. SN - 1471-2199 UR - https://doi.org/10.1186/s12867-017-0090-3 DO - 10.1186/s12867-017-0090-3 ID - Croft2017 ER -