TY - JOUR AU - Veres-Székely, Apor AU - Pap, Domonkos AU - Sziksz, Erna AU - Jávorszky, Eszter AU - Rokonay, Réka AU - Lippai, Rita AU - Tory, Kálmán AU - Fekete, Andrea AU - Tulassay, Tivadar AU - Szabó, Attila J. AU - Vannay, Ádám PY - 2017 DA - 2017/04/27 TI - Selective measurement of α smooth muscle actin: why β-actin can not be used as a housekeeping gene when tissue fibrosis occurs JO - BMC Molecular Biology SP - 12 VL - 18 IS - 1 AB - Prevalence of fibroproliferative diseases, including chronic kidney disease is rapidly increasing and has become a major public health problem worldwide. Fibroproliferative diseases are characterized by increased expression of α smooth muscle actin (α-SMA) that belongs to the family of the six conserved actin isoforms showing high degree homology. The aim of the present study was to develop real-time PCRs that clearly discriminate α-SMA and ß-actin from other actin isoforms. SN - 1471-2199 UR - https://doi.org/10.1186/s12867-017-0089-9 DO - 10.1186/s12867-017-0089-9 ID - Veres-Székely2017 ER -