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Fig. 10 | BMC Molecular Biology

Fig. 10

From: Properties of STAT1 and IRF1 enhancers and the influence of SNPs

Fig. 10

SNPs modulate STAT1 and IRF1 binding in vitro. a IRF1, and: b STAT1 binding assays. Graphs show STAT1 and IRF1 binding signal to immobilized probes in the presence of different concentrations of competitor probes with either the variant or reference allele. 100% binding is that obtained in the absence of competitor. Arrows highlight the affected base (or 4 bases in the control mutated probe). As indicated, rs9260102 was also assessed in vivo (Fig. 11)

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