Table 6 Putative xenobiotic metabolism-related target genes of A. gossypii miRNAs

Ago-miR-1-3p

G-protein coupled receptor

Ago-miR-341b-5p

Acetylcholinesterase, CYP6A8, CYP6A14

Ago-miR-656a-3p

CYP6J1, glutathione S-transferase sigma 1, carboxylesterase

Ago-miR-669c-5p

CYP6J1, glutathione S-transferase sigma 1

Ago-miR-1181

CYP6A13

Ago-miR-1332-3p

UDP-glucuronosyltransferase, CYP6A8, CYP6K1, CYP4C1, CYP6A2, CYP6A13

Ago-miR-1946a

Acetylcholinesterase, glutathione S-transferase omega 1

Ago-miR-2886

Acetylcholinesterase

Ago-miR-2899a

CYP18A1

Ago-miR-3163

Glutathione S-transferase sigma 1

Ago-miR-3191-3p

Carboxylesterase

Ago-miR-3575

CYP315A1, glutathione S-transferase sigma 2

Ago-miR-4172-3p

CYP6J1, glutathione S-transferase sigma 1

Ago-miR-4213-5p

Carboxylesterase, glutathione S-transferase sigma 2

Ago-miR-466la-3p

Carboxylesterase

Ago-miR-4467a-1

Sodium channel protein, calcium channel flower, CYP6A8, ryanodine receptor 44F, gamma-aminobutyric acid receptor, voltage-dependent calcium channel type A subunit alpha 1, nicotinic acetylcholine receptor alpha subunit

Ago-miR-4467a-2

CYP6A2, CYP6A8, esterase FE4, ryanodine receptor 44F

Ago-miR-4783-5p

Glutamate-gated chloride channel, voltage-dependent T-type calcium channel subunit alpha 1

Ago-miR-4973a-1-5p

Ryanodine receptor

Ago-miR-4973-5p-11

Ryanodine receptor 44F, sodium channel protein para, voltage-dependent L-type calcium channel subunit beta 2, Nic acetylcholine receptor alpha 2, Glutamate-gated chloride channel, Voltage-dependent T-type calcium channel subunit alpha 1

Ago-miR-4973 g-5p

Acetylcholinesterase, CYP6K1

Ago-miR-6236

Voltage-dependent calcium channel type A subunit alpha 1

Ago-miR-6850-3p-1

CYP6A8

Ago-miR-7475a-5p

Venom carboxylesterase-6

Ago-miR-8798a

CYP6A8

Ago-miR-8798c

Voltage-dependent calcium channel type A subunit alpha 1

Ago-novel-7

Sodium channel protein 60E, CYP6A8, UDP-glucuronosyltransferase

Ago-novel-10a

Ryanodine receptor 44F

Ago-novel-16

CYP18A1

Ago-novel-19

Acetylcholinesterase, CYP6A8, CYP6A2

Ago-novel-24

Acetylcholinesterase, CYP6A8

Ago-novel-28

Voltage-dependent calcium channel type A subunit alpha 1