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Fig. 1 | BMC Molecular Biology

Fig. 1

From: Heterogeneous pattern of DNA methylation in developmentally important genes correlates with its chromatin conformation

Fig. 1

a Schematic diagram showing methylated CpG (dark circles) sites in the coding region of c-mos gene b Quantitative real-time PCR for analysis of relative gene expression in c-mos gene for different tissue types. Experiments were performed thrice independently. All results are shown as the mean ± S.D and are considered significant at P < 0.05. c Line diagram shows methylation pattern of total 25 CpG sites in the regulatory region of c-mos gene. Each individual line represents specific clone consisting of 25 CpG sites. Methylated CpGs are denoted by dark circles while non-methylated ones are denoted by white circles (upper panel). Graph represents percentage methylation in individual sites for adult testis, d adult ovary and e adult kidney respectively (lower panel) f–i Graph shows percentage input and fold enrichment done by ChIP-qPCR to assess the H3K4me3 and H3K9me3 occupancy of c-mos gene in adult testis and adult kidney. Error bar represents the mean ± SD

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