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Fig. 4 | BMC Molecular Biology

Fig. 4

From: A potential role for protein palmitoylation and zDHHC16 in DNA damage response

Fig. 4

Inhibition of palmitoylation impaired assembly/disassembly of DNA damage foci. Primary MEFs grown on coverslips were pre-treated with 50 μM 2BP for 24 h and then treated with 1 μM Dox for different periods of time. The cells were then fixed and immune-stained for H2AX using Texas-red conjugated secondary antibodies (a). b Averaged number of foci per cell from multiple repeated experiments and multiple cells per experiment. Asterisk denoted significant difference (p < 0.05) between compared groups

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